TY  - JOUR
AU  - Komsiyska, L.
AU  - Tsakova, V.
AU  - Staikov, G.
TI  - Electrochemical Formation and Properties of Thin Polyaniline Films on Au(111) and p-Si(111)
JO  - Applied physics / A
VL  - 87
SN  - 0947-8396
CY  - Berlin
PB  - Springer
M1  - PreJuSER-58660
SP  - 405 - 409
PY  - 2007
N1  - Record converted from VDB: 12.11.2012
AB  - In hypertensive subjects, it has been demonstrated that the lower the blood pressure, the lower the incidence of chronic kidney disease (CKD). However, whether this relationship holds true in individuals without hypertension--that is, in individuals with a blood pressure <140/90 mmHg--remains unknown. This study was performed to assess the relationship between blood pressure and CKD in a Japanese population without hypertension. Among 13,007 Japanese participants in a general health screening, 9,596 (5,691 men and 3,905 women) were found to have either normal blood pressure or prehypertension, and were enrolled in this study. We categorized these individuals' blood pressure into six classes: BP-C1, <90/<65 mmHg; BP-C2, 90-100/65-70 mmHg; BP-C3, 100-110/70-75 mmHg; BP-C4, 110-120/75-80 mmHg; BP-C5, 120-130/80-85 mmHg; and BP-C6, 130-140/85-90 mmHg. Albuminuria was defined as a urinary albumin excretion ratio of > or =30 mg/g. Low estimated glomerular filtration rate (eGFR) was defined as eGFR <60 mL/min/1.73 m2. In men, when BP-C3 was used as a reference, multivariate logistic regression analysis adjusted for age, body mass index, serum lipid profiles, fasting plasma glucose and smoking status showed that BP-C1, BP-C2, BP-C4, BP-C5 and BP-C6 were associated with albuminuria with an adjusted odds ratio of 1.85 (0.53-6.46), 1.22 (0.59-2.51), 1.62 (1.01-2.59), 2.57 (1.64-4.02), and 3.81 (2.44-5.96). In women, the adjusted odds ratios of the risk for albuminuria in BP-C2, BP-C3, BP-C4, BP-C5 and BP-C6, as compared with BP-C1 as a reference, were 1.83 (0.70-4.79), 2.13 (0.84-5.42), 2.80 (1.10-7.14), 2.59 (0.99-6.78), and 3.99 (1.50-10.64). Blood pressure was not significantly associated with low eGFR in either gender. The risk for albuminuria was significantly greater when blood pressure exceeded 110/75 mmHg in both genders.
KW  - Adult
KW  - Aged
KW  - Albuminuria: epidemiology
KW  - Albuminuria: physiopathology
KW  - Blood Pressure
KW  - Chronic Disease
KW  - Female
KW  - Glomerular Filtration Rate
KW  - Humans
KW  - Hypertension: complications
KW  - Kidney Diseases: etiology
KW  - Kidney Diseases: physiopathology
KW  - Male
KW  - Middle Aged
KW  - Prevalence
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:18360039
UR  - <Go to ISI:>//WOS:000244950900010
DO  - DOI:10.1007/s00339-007-3905-0
UR  - https://juser.fz-juelich.de/record/58660
ER  -