TY  - JOUR
AU  - Schleicher, A.
AU  - Morosan, P.
AU  - Amunts, K.
AU  - Zilles, K.
TI  - Quantitative Architectural Analysis: A New Approach to Cortical Mapping
JO  - Journal of autism and developmental disorders
VL  - 39
SN  - 0162-3257
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V.
M1  - PreJuSER-5999
SP  - 1568 - 1581
PY  - 2009
N1  - Record converted from VDB: 12.11.2012
AB  - Results from functional imaging studies are often still interpreted using the classical architectonic brain maps of Brodmann and his successors. One obvious weakness in traditional, architectural mapping is the subjective nature of localizing borders between cortical areas by means of a purely visual, microscopical examination of histological specimens. To overcome this limitation, objective mapping procedures based on quantitative cytoarchitecture have been generated. As a result, new maps for various species including man were established. In our contribution, principles of quantitative cytoarchitecture and algorithm-based cortical mapping are described for a cytoarchitectural parcellation of the human auditory cortex. Defining cortical borders based on quantified changes in cortical lamination is the decisive step towards a novel, highly improved probabilistic brain atlas.
KW  - Auditory Cortex: physiology
KW  - Brain Mapping: methods
KW  - Cell Count
KW  - Cerebral Cortex: cytology
KW  - Cerebral Cortex: physiology
KW  - Humans
KW  - Pyramidal Cells: physiology
KW  - Temporal Lobe: physiology
LB  - PUB:(DE-HGF)16
C6  - pmid:19582566
UR  - <Go to ISI:>//WOS:000270669300008
DO  - DOI:10.1007/s10803-009-0790-8
UR  - https://juser.fz-juelich.de/record/5999
ER  -