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000006002 0247_ $$2DOI$$a10.1016/j.sleep.2007.12.003
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000006002 041__ $$aeng
000006002 082__ $$a610
000006002 084__ $$2WoS$$aClinical Neurology
000006002 1001_ $$0P:(DE-Juel1)131679$$aElmenhorst, D.$$b0$$uFZJ
000006002 245__ $$aPerformance impairment during four days partial sleep deprivation compared with the acute effects of alcohol and hypoxia
000006002 260__ $$aAmsterdam [u.a.]$$bElsevier$$c2009
000006002 300__ $$a189 - 197
000006002 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000006002 440_0 $$021281$$aSleep Medicine$$v10$$x1389-9457$$y2
000006002 500__ $$aThe authors gratefully thank Astrid Linke-Hommes, Louise Mawet, Gernot Plath and Manfred Schulze for their support of this work. The project was supported by the "Deutsche Akademie fur Flug-und Reisemedizin".
000006002 520__ $$aSubjects were exposed to cumulated partial sleep deprivation (psd), alcohol intake and hypoxia in a sequential design to examine the impact on neurobehavioral performance.Sixteen healthy male volunteers were enrolled in this study and were exposed in turn, after adaptation and baseline measurements, to one day of periods of hypoxia, one day of alcohol intake and one day for recovering (with 8h time in bed TIB). Subsequently the exposition of those conditions is that the subjects spent 5h night restriction daily for four consecutive days, followed by two recovery days. Performance was tested five (or six) times per day with reaction time task (SRT) and unstable tracking task (UTT).The performance impairment showed to be cumulative in both tests over the four sleep deprivation days and differed significantly from baseline. Corresponding performance deficits under the influence of the stressors were for SRT: four days psd, 13% O(2) concentration and a blood alcohol concentration (BAC) of around 0.4-0.6 per thousand for UTT: four days psd, 13% O(2) concentration and a BAC of around 0.6 per thousand. One night of 8h sleep restored performance nearly to baseline level.A sleeping time of 5h per night for four consecutive days impairs performance in such a way that traffic safety may be compromised.
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000006002 650_2 $$2MeSH$$aAdult
000006002 650_2 $$2MeSH$$aAlcoholic Intoxication: complications
000006002 650_2 $$2MeSH$$aAlcoholic Intoxication: physiopathology
000006002 650_2 $$2MeSH$$aAlcoholic Intoxication: psychology
000006002 650_2 $$2MeSH$$aAnoxia: complications
000006002 650_2 $$2MeSH$$aAnoxia: physiopathology
000006002 650_2 $$2MeSH$$aAnoxia: psychology
000006002 650_2 $$2MeSH$$aHumans
000006002 650_2 $$2MeSH$$aMale
000006002 650_2 $$2MeSH$$aPsychomotor Performance: physiology
000006002 650_2 $$2MeSH$$aReaction Time
000006002 650_2 $$2MeSH$$aRecovery of Function
000006002 650_2 $$2MeSH$$aRisk Factors
000006002 650_2 $$2MeSH$$aSleep Deprivation: complications
000006002 650_2 $$2MeSH$$aSleep Deprivation: physiopathology
000006002 650_2 $$2MeSH$$aSleep Deprivation: psychology
000006002 650_2 $$2MeSH$$aTime Factors
000006002 650_2 $$2MeSH$$aYoung Adult
000006002 650_7 $$2WoSType$$aJ
000006002 65320 $$2Author$$aPartial sleep deprivation
000006002 65320 $$2Author$$aAlcohol
000006002 65320 $$2Author$$aHypoxia
000006002 65320 $$2Author$$aPerformance
000006002 65320 $$2Author$$aReaction time
000006002 65320 $$2Author$$aUnstable tracking
000006002 7001_ $$0P:(DE-HGF)0$$aElmenhorst, E.M.$$b1
000006002 7001_ $$0P:(DE-HGF)0$$aLuks, N.$$b2
000006002 7001_ $$0P:(DE-HGF)0$$aMaass, H.$$b3
000006002 7001_ $$0P:(DE-HGF)0$$aMueller, E.W.$$b4
000006002 7001_ $$0P:(DE-HGF)0$$aVejvoda, M.$$b5
000006002 7001_ $$0P:(DE-HGF)0$$aWenzel, J.$$b6
000006002 7001_ $$0P:(DE-HGF)0$$aSamel, A.$$b7
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000006002 8567_ $$uhttp://dx.doi.org/10.1016/j.sleep.2007.12.003
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