TY  - JOUR
AU  - Elmenhorst, D.
AU  - Elmenhorst, E.M.
AU  - Luks, N.
AU  - Maass, H.
AU  - Mueller, E.W.
AU  - Vejvoda, M.
AU  - Wenzel, J.
AU  - Samel, A.
TI  - Performance impairment during four days partial sleep deprivation compared with the acute effects of alcohol and hypoxia
JO  - Sleep medicine
VL  - 10
SN  - 1389-9457
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - PreJuSER-6002
SP  - 189 - 197
PY  - 2009
N1  - The authors gratefully thank Astrid Linke-Hommes, Louise Mawet, Gernot Plath and Manfred Schulze for their support of this work. The project was supported by the "Deutsche Akademie fur Flug-und Reisemedizin".
AB  - Subjects were exposed to cumulated partial sleep deprivation (psd), alcohol intake and hypoxia in a sequential design to examine the impact on neurobehavioral performance.Sixteen healthy male volunteers were enrolled in this study and were exposed in turn, after adaptation and baseline measurements, to one day of periods of hypoxia, one day of alcohol intake and one day for recovering (with 8h time in bed TIB). Subsequently the exposition of those conditions is that the subjects spent 5h night restriction daily for four consecutive days, followed by two recovery days. Performance was tested five (or six) times per day with reaction time task (SRT) and unstable tracking task (UTT).The performance impairment showed to be cumulative in both tests over the four sleep deprivation days and differed significantly from baseline. Corresponding performance deficits under the influence of the stressors were for SRT: four days psd, 13% O(2) concentration and a blood alcohol concentration (BAC) of around 0.4-0.6 per thousand for UTT: four days psd, 13% O(2) concentration and a BAC of around 0.6 per thousand. One night of 8h sleep restored performance nearly to baseline level.A sleeping time of 5h per night for four consecutive days impairs performance in such a way that traffic safety may be compromised.
KW  - Adult
KW  - Alcoholic Intoxication: complications
KW  - Alcoholic Intoxication: physiopathology
KW  - Alcoholic Intoxication: psychology
KW  - Anoxia: complications
KW  - Anoxia: physiopathology
KW  - Anoxia: psychology
KW  - Humans
KW  - Male
KW  - Psychomotor Performance: physiology
KW  - Reaction Time
KW  - Recovery of Function
KW  - Risk Factors
KW  - Sleep Deprivation: complications
KW  - Sleep Deprivation: physiopathology
KW  - Sleep Deprivation: psychology
KW  - Time Factors
KW  - Young Adult
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:18276188
UR  - <Go to ISI:>//WOS:000264683300007
DO  - DOI:10.1016/j.sleep.2007.12.003
UR  - https://juser.fz-juelich.de/record/6002
ER  -