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@ARTICLE{Elmenhorst:6002,
      author       = {Elmenhorst, D. and Elmenhorst, E.M. and Luks, N. and Maass,
                      H. and Mueller, E.W. and Vejvoda, M. and Wenzel, J. and
                      Samel, A.},
      title        = {{P}erformance impairment during four days partial sleep
                      deprivation compared with the acute effects of alcohol and
                      hypoxia},
      journal      = {Sleep medicine},
      volume       = {10},
      issn         = {1389-9457},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {PreJuSER-6002},
      pages        = {189 - 197},
      year         = {2009},
      note         = {The authors gratefully thank Astrid Linke-Hommes, Louise
                      Mawet, Gernot Plath and Manfred Schulze for their support of
                      this work. The project was supported by the "Deutsche
                      Akademie fur Flug-und Reisemedizin".},
      abstract     = {Subjects were exposed to cumulated partial sleep
                      deprivation (psd), alcohol intake and hypoxia in a
                      sequential design to examine the impact on neurobehavioral
                      performance.Sixteen healthy male volunteers were enrolled in
                      this study and were exposed in turn, after adaptation and
                      baseline measurements, to one day of periods of hypoxia, one
                      day of alcohol intake and one day for recovering (with 8h
                      time in bed TIB). Subsequently the exposition of those
                      conditions is that the subjects spent 5h night restriction
                      daily for four consecutive days, followed by two recovery
                      days. Performance was tested five (or six) times per day
                      with reaction time task (SRT) and unstable tracking task
                      (UTT).The performance impairment showed to be cumulative in
                      both tests over the four sleep deprivation days and differed
                      significantly from baseline. Corresponding performance
                      deficits under the influence of the stressors were for SRT:
                      four days psd, $13\%$ O(2) concentration and a blood alcohol
                      concentration (BAC) of around 0.4-0.6 per thousand for UTT:
                      four days psd, $13\%$ O(2) concentration and a BAC of around
                      0.6 per thousand. One night of 8h sleep restored performance
                      nearly to baseline level.A sleeping time of 5h per night for
                      four consecutive days impairs performance in such a way that
                      traffic safety may be compromised.},
      keywords     = {Adult / Alcoholic Intoxication: complications / Alcoholic
                      Intoxication: physiopathology / Alcoholic Intoxication:
                      psychology / Anoxia: complications / Anoxia: physiopathology
                      / Anoxia: psychology / Humans / Male / Psychomotor
                      Performance: physiology / Reaction Time / Recovery of
                      Function / Risk Factors / Sleep Deprivation: complications /
                      Sleep Deprivation: physiopathology / Sleep Deprivation:
                      psychology / Time Factors / Young Adult / J (WoSType)},
      cin          = {INM-2},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      shelfmark    = {Clinical Neurology},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:18276188},
      UT           = {WOS:000264683300007},
      doi          = {10.1016/j.sleep.2007.12.003},
      url          = {https://juser.fz-juelich.de/record/6002},
}