TY  - JOUR
AU  - Semmrich, C.
AU  - Storz, T.
AU  - Glaser, J.
AU  - Merkel, R.
AU  - Bausch, A. R.
AU  - Kroy, K.
TI  - Glass transition and rheological redundancy in F-actin solutions (from the cover)
JO  - Proceedings of the National Academy of Sciences of the United States of America
VL  - 104
SN  - 0027-8424
CY  - Washington, DC
PB  - Academy
M1  - PreJuSER-60039
SP  - 20199 - 20203
PY  - 2007
N1  - Record converted from VDB: 12.11.2012
AB  - The unique mechanical performance of animal cells and tissues is attributed mostly to their internal biopolymer meshworks. Its perplexing universality and robustness against structural modifications by drugs and mutations is an enigma in cell biology and provides formidable challenges to materials science. Recent investigations could pinpoint highly universal patterns in the soft glassy rheology and nonlinear elasticity of cells and reconstituted networks. Here, we report observations of a glass transition in semidilute F-actin solutions, which could hold the key to a unified explanation of these phenomena. Combining suitable rheological protocols with high-precision dynamic light scattering, we can establish a remarkable rheological redundancy and trace it back to a highly universal exponential stretching of the single-polymer relaxation spectrum of a "glassy wormlike chain." By exploiting the ensuing generalized time-temperature superposition principle, the time domain accessible to microrheometry can be extended by several orders of magnitude, thus opening promising new metrological opportunities.
KW  - Actins: chemistry
KW  - Animals
KW  - Glass: chemistry
KW  - Phase Transition
KW  - Rabbits
KW  - Rheology
KW  - Solutions
KW  - Temperature
KW  - Actins (NLM Chemicals)
KW  - Solutions (NLM Chemicals)
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:18077385
C2  - pmc:PMC2154408
UR  - <Go to ISI:>//WOS:000251885000011
DO  - DOI:10.1073/pnas.0705513104
UR  - https://juser.fz-juelich.de/record/60039
ER  -