%0 Journal Article %A Babay, P. A. %A Ale, E. E. R. %A Itria, R. F. %A Becquart, E. T. %A Thiele, B. %A Batistoni, D. A. %T Simplified determination of lipophilic metabolites of nonylphenol ethoxylates: method development and application in aqueous samples from Buenos Aires, Argentina %J Journal of environmental monitoring %V 10 %@ 1464-0325 %C London %I Royal Society of Chemistry %M PreJuSER-61335 %P 443 - 452 %D 2008 %Z Record converted from VDB: 12.11.2012 %X In the present work we have developed an analytical methodology for the determination of nonylphenol (NP) and nonylphenol mono- and di-ethoxylates (NP1EO and NP2EO) in water samples. The applicability of this methodology was proved by means of the analysis of environmentally relevant aqueous samples from Buenos Aires. This constitutes a starting point for a rigorous assessment of the incidence of NPnEO surfactants in Argentina, as only very few, qualitative or semi-quantitative data on the occurrence of these compounds in local systems were available up to this time. Enrichment of the analytes was carried out by solid-phase extraction on a C-18 sorbent, followed by elution with ethyl acetate. Normal-phase high performance liquid chromatography on an amino-silica column and fluorescence detection at excitation-emission wavelengths of 230-300 nm were employed for separation and quantification of the analytes. Confirmation of peak assignment in selected real samples was performed by off-line coupling HPLC with GC-MS analysis. A non-polar GC capillary column was used, and a characteristic peak pattern was obtained for the alkyl chain isomers of each ethoxylated homologue and NP. GC-MS analyses yielded in all cases purity levels higher than 80% for the HPLC collected fractions. The elevated concentrations found for the estrogenic metabolites of NPnEO are in accordance with an unrestricted use of this class of non-ionic surfactants in the country. %K Argentina %K Chromatography, High Pressure Liquid %K Environmental Monitoring: methods %K Ethylene Glycols: analysis %K Gas Chromatography-Mass Spectrometry %K Solid Phase Extraction %K Surface-Active Agents: analysis %K Water Pollutants, Chemical: analysis %K Ethylene Glycols (NLM Chemicals) %K Surface-Active Agents (NLM Chemicals) %K Water Pollutants, Chemical (NLM Chemicals) %K terics (NLM Chemicals) %K J (WoSType) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:18385865 %U <Go to ISI:>//WOS:000254648300007 %R 10.1039/b717942a %U https://juser.fz-juelich.de/record/61335