TY - JOUR AU - Babay, P. A. AU - Ale, E. E. R. AU - Itria, R. F. AU - Becquart, E. T. AU - Thiele, B. AU - Batistoni, D. A. TI - Simplified determination of lipophilic metabolites of nonylphenol ethoxylates: method development and application in aqueous samples from Buenos Aires, Argentina JO - Journal of environmental monitoring VL - 10 SN - 1464-0325 CY - London PB - Royal Society of Chemistry M1 - PreJuSER-61335 SP - 443 - 452 PY - 2008 N1 - Record converted from VDB: 12.11.2012 AB - In the present work we have developed an analytical methodology for the determination of nonylphenol (NP) and nonylphenol mono- and di-ethoxylates (NP1EO and NP2EO) in water samples. The applicability of this methodology was proved by means of the analysis of environmentally relevant aqueous samples from Buenos Aires. This constitutes a starting point for a rigorous assessment of the incidence of NPnEO surfactants in Argentina, as only very few, qualitative or semi-quantitative data on the occurrence of these compounds in local systems were available up to this time. Enrichment of the analytes was carried out by solid-phase extraction on a C-18 sorbent, followed by elution with ethyl acetate. Normal-phase high performance liquid chromatography on an amino-silica column and fluorescence detection at excitation-emission wavelengths of 230-300 nm were employed for separation and quantification of the analytes. Confirmation of peak assignment in selected real samples was performed by off-line coupling HPLC with GC-MS analysis. A non-polar GC capillary column was used, and a characteristic peak pattern was obtained for the alkyl chain isomers of each ethoxylated homologue and NP. GC-MS analyses yielded in all cases purity levels higher than 80% for the HPLC collected fractions. The elevated concentrations found for the estrogenic metabolites of NPnEO are in accordance with an unrestricted use of this class of non-ionic surfactants in the country. KW - Argentina KW - Chromatography, High Pressure Liquid KW - Environmental Monitoring: methods KW - Ethylene Glycols: analysis KW - Gas Chromatography-Mass Spectrometry KW - Solid Phase Extraction KW - Surface-Active Agents: analysis KW - Water Pollutants, Chemical: analysis KW - Ethylene Glycols (NLM Chemicals) KW - Surface-Active Agents (NLM Chemicals) KW - Water Pollutants, Chemical (NLM Chemicals) KW - terics (NLM Chemicals) KW - J (WoSType) LB - PUB:(DE-HGF)16 C6 - pmid:18385865 UR - <Go to ISI:>//WOS:000254648300007 DO - DOI:10.1039/b717942a UR - https://juser.fz-juelich.de/record/61335 ER -