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| 001 | 6186 | ||
| 005 | 20180208231534.0 | ||
| 024 | 7 | _ | |a 10.1149/1.3206642 |2 DOI |
| 024 | 7 | _ | |a 0013-4651 |2 ISSN |
| 024 | 7 | _ | |a 0096-4743 |2 ISSN |
| 024 | 7 | _ | |a 0096-4786 |2 ISSN |
| 024 | 7 | _ | |a 1945-7111 |2 ISSN |
| 024 | 7 | _ | |a WOS:000338086300041 |2 WOS |
| 037 | _ | _ | |a PreJuSER-6186 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 540 |
| 100 | 1 | _ | |a Waser, R. |b 0 |u FZJ |0 P:(DE-Juel1)131022 |
| 245 | _ | _ | |a Electrochemical reactions in nanoionics - towards future resistive switching memories |
| 260 | _ | _ | |a Pennington, NJ |b Electrochemical Society |c 2009 |
| 300 | _ | _ | |a 431 - 437 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |a Journal of the Electrochemical Society |x 0013-4651 |0 3889 |y 6 |v 25 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a This open-label extension evaluated the long-term efficacy and tolerability of rufinamide in patients with Lennox-Gastaut syndrome (LGS) who had previously completed a 12-week double-blind study.In total, 124 patients (aged 4-37 years), receiving 1-3 concomitant antiepileptic drugs, were treated with rufinamide approximately 25-60 mg/kg/day. Efficacy was assessed by seizure frequency; tolerability by adverse events (AEs) and laboratory tests.Overall, patients were treated with rufinamide for a median (range) of 432 (10-1149) days. Reductions in seizure frequency were observed throughout the study; during the last 12 months of treatment, 41.0% and 47.9% of patients had > or = 50% reduction in total and tonic-atonic seizure frequency, respectively. The most common AEs were vomiting (30.6%) and pyrexia (25.8%).In this open-label extension, rufinamide appeared to be an effective long-term adjunctive therapy for the treatment of LGS-associated seizures in children and young adults. |
| 536 | _ | _ | |a Grundlagen für zukünftige Informationstechnologien |c P42 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK412 |x 0 |
| 588 | _ | _ | |a Dataset connected to Pubmed |
| 700 | 1 | _ | |a Valov, I. |b 1 |u FZJ |0 P:(DE-Juel1)VDB85752 |
| 773 | _ | _ | |a 10.1149/1.3206642 |g Vol. 25, p. 431 - 437 |p 431 - 437 |q 25<431 - 437 |0 PERI:(DE-600)2002179-3 |t Journal of the Electrochemical Society |v 25 |y 2009 |x 0013-4651 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1149/1.3206642 |
| 909 | C | O | |o oai:juser.fz-juelich.de:6186 |p VDB |
| 913 | 1 | _ | |k P42 |v Grundlagen für zukünftige Informationstechnologien |l Grundlagen für zukünftige Informationstechnologien (FIT) |b Schlüsseltechnologien |0 G:(DE-Juel1)FUEK412 |x 0 |
| 914 | 1 | _ | |y 2009 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 920 | 1 | _ | |d 31.12.2010 |g IFF |k IFF-6 |l Elektronische Materialien |0 I:(DE-Juel1)VDB786 |x 0 |
| 920 | 1 | _ | |0 I:(DE-82)080009_20140620 |k JARA-FIT |l Jülich-Aachen Research Alliance - Fundamentals of Future Information Technology |g JARA |x 1 |
| 970 | _ | _ | |a VDB:(DE-Juel1)114330 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)PGI-7-20110106 |
| 980 | _ | _ | |a I:(DE-82)080009_20140620 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)PGI-7-20110106 |
| 981 | _ | _ | |a I:(DE-Juel1)VDB881 |
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