TY  - JOUR
AU  - Waberski, T. D.
AU  - Gobbelé, R.
AU  - Lamberty, K.
AU  - Buchner, H.
AU  - Marshall, J. C.
AU  - Fink, G. R.
TI  - Timing of visuo-spatial information processing: Electrical source imaging related to line bisection judgements
JO  - Neuropsychologia
VL  - 46
SN  - 0028-3932
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - PreJuSER-61918
SP  - 1201 - 1210
PY  - 2008
N1  - Record converted from VDB: 12.11.2012
AB  - This study deconvolves the temporal dynamics of the neural processes underlying line bisection judgements (i.e., the landmark task). Event-related potentials (ERPs) were recorded from 96 scalp electrodes in 10 healthy right-handed male subjects while they were judging whether horizontal lines were correctly prebisected. In the control task, subjects judged whether or not the horizontal line was transected by a vertical line, irrespective of its position. Using a current density reconstruction approach, source maxima in the time range from 50 to 400ms after stimulus onset were localized and the time courses of activation were elaborated. Five regions, corresponding to those revealed by our previous fMRI studies (e.g., [Fink, G. R., Marshall, J. C., Shah, N. J., Weiss, P. H., Halligan, P. W., Grosse-Ruyken, et al. (2000). Line bisection judgments implicate right parietal cortex and cerebellum as assessed by fMRI. Neurology, 54, 1324-1331]), were identified as contributing significant source activity related to line bisection judgements: right middle occipital gyrus (Brodmann area; BA18); bilateral inferior occipital gyrus (BA19); right superior posterior parietal cortex (BA7) and right inferior posterior parietal cortex (BA40). Temporal deconvolution indicated sequential activation of these regions starting at BA18 as early as 90ms post-stimulus onset, followed by the successive activation of the right superior posterior parietal (BA7), bilateral inferior occipital (BA19) and right inferior posterior parietal cortex (BA40). Three of these areas (BA18, BA17 and BA19) became reactivated within 250ms of stimulus onset. The data provide evidence for an early involvement of the right hemispheric parietal network in visuo-spatial information processing. Furthermore, the temporal deconvolution of the electrophysiological data suggest that iterative processes between and within parietal (dorsal path) and occipital areas (ventral path) mediate bisection judgements.
KW  - Adult
KW  - Algorithms
KW  - Cluster Analysis
KW  - Data Interpretation, Statistical
KW  - Electroencephalography
KW  - Evoked Potentials: physiology
KW  - Head
KW  - Humans
KW  - Image Processing, Computer-Assisted
KW  - Male
KW  - Models, Anatomic
KW  - Models, Neurological
KW  - Psychometrics
KW  - Psychomotor Performance: physiology
KW  - Reaction Time: physiology
KW  - Space Perception: physiology
KW  - Visual Cortex: physiology
KW  - Visual Perception: physiology
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:18249421
UR  - <Go to ISI:>//WOS:000256789500002
DO  - DOI:10.1016/j.neuropsychologia.2007.10.024
UR  - https://juser.fz-juelich.de/record/61918
ER  -