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000062370 041__ $$aeng
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000062370 1001_ $$0P:(DE-Juel1)129343$$aKastenholz, B.$$b0$$uFZJ
000062370 245__ $$aPhytochemical approach and bioanalytical strategy to develop chaperone-based medications
000062370 260__ $$aSharjah [u.a.]$$bBentham Open$$c2008
000062370 300__ $$a44 - 48
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000062370 440_0 $$018801$$aThe Open Biochemistry Journal$$v2$$x1874-091X
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000062370 520__ $$aCurrently, no pharmaceuticals for the etiological treatment of degenerative protein-misfolding diseases (e.g., ALS, Alzheimer's or prion diseases) are commercially available. In this technical note theoretical considerations and practical approaches concerning the development of chaperone-based medications from medicinal plants (e.g., Ginkgo biloba) are reviewed and discussed in detail. Phytochaperones and other agents isolated from medicinal plants are proposed to serve as the general basis of drug development in protein-misfolding diseases.
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000062370 773__ $$0PERI:(DE-600)2396170-3$$a10.2174/1874091X00802010044$$gVol. 2, p. 44 - 48$$p44 - 48$$q2<44 - 48$$tThe @open biochemistry journal$$v2$$x1874-091X$$y2008
000062370 8567_ $$2Pubmed Central$$uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570550
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000062370 9141_ $$y2008
000062370 915__ $$0StatID:(DE-HGF)0020$$aNo peer review
000062370 9201_ $$0I:(DE-Juel1)ICG-3-20090406$$d31.10.2010$$gICG$$kICG-3$$lPhytosphäre$$x1
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