TY  - JOUR
AU  - Kastenholz, B.
TI  - Phytochemical approach and bioanalytical strategy to develop chaperone-based medications
JO  - The open biochemistry journal
VL  - 2
SN  - 1874-091X
CY  - Sharjah [u.a.]
PB  - Bentham Open
M1  - PreJuSER-62370
SP  - 44 - 48
PY  - 2008
N1  - Record converted from VDB: 12.11.2012
AB  - Currently, no pharmaceuticals for the etiological treatment of degenerative protein-misfolding diseases (e.g., ALS, Alzheimer's or prion diseases) are commercially available. In this technical note theoretical considerations and practical approaches concerning the development of chaperone-based medications from medicinal plants (e.g., Ginkgo biloba) are reviewed and discussed in detail. Phytochaperones and other agents isolated from medicinal plants are proposed to serve as the general basis of drug development in protein-misfolding diseases.
LB  - PUB:(DE-HGF)16
C6  - pmid:18949074
C2  - pmc:PMC2570550
DO  - DOI:10.2174/1874091X00802010044
UR  - https://juser.fz-juelich.de/record/62370
ER  -