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@ARTICLE{Metzner:62912,
author = {Metzner, R. and Schneider, H. U. and Breuer, U. and
Schröder, W. H.},
title = {{I}maging {N}utrient {D}istributions in {P}lant {T}issue
{U}sing {T}ime-of-{F}light {S}econdary {I}on {M}ass
{S}pectrometry and {S}canning {E}lectron {M}icroscopy},
journal = {Plant physiology},
volume = {147},
issn = {0032-0889},
address = {Rockville, Md.: Soc.},
publisher = {JSTOR},
reportid = {PreJuSER-62912},
pages = {1774 - 1787},
year = {2008},
note = {Record converted from VDB: 12.11.2012},
abstract = {A new approach to trace the transport routes of
macronutrients in plants at the level of cells and tissues
and to measure their elemental distributions was developed
for investigating the dynamics and structure-function
relationships of transport processes. Stem samples from
Phaseolus vulgaris were used as a test system. Shock
freezing and cryo-preparation were combined in a cryogenic
chain with cryo-time-of-flight secondary ion mass
spectrometry (cryo-ToF-SIMS) for element and
isotope-specific imaging. Cryo-scanning electron microscopy
(cryo-SEM) was integrated into the cryogenic workflow to
assess the quality of structural preservation. We evaluated
the capability of these techniques to monitor transport
pathways and processes in xylem and associated tissues using
supplementary sodium (Na) and tracers for potassium (K),
rubidium (Rb), and (41)K added to the transpiration stream.
Cryo-ToF-SIMS imaging produced detailed mappings of water,
K, calcium, magnesium, the K tracers, and Na without
quantification. Lateral resolutions ranged from 10 microm in
survey mappings and at high mass resolution to approximately
1 microm in high lateral resolution imaging in reduced areas
and at lower mass resolution. The tracers Rb and (41)K, as
well as Na, were imaged with high sensitivity in xylem
vessels and surrounding tissues. The isotope signature of
the stable isotope tracer was utilized for relative
quantification of the (41)K tracer as a fraction of total K
at the single pixel level. Cryo-SEM confirmed that tissue
structures had been preserved with subcellular detail
throughout all procedures. Overlays of cryo-ToF-SIMS images
onto the corresponding SEM images allowed detailed
correlation of nutrient images with subcellular structures.},
keywords = {Biological Transport / Cryoelectron Microscopy: methods /
Microscopy, Electron, Scanning: methods / Phaseolus:
chemistry / Phaseolus: metabolism / Phaseolus:
ultrastructure / Plant Stems: chemistry / Plant
Transpiration / Potassium: analysis / Potassium: metabolism
/ Potassium Isotopes / Rubidium: analysis / Rubidium:
metabolism / Sodium: analysis / Sodium: metabolism /
Spectrometry, Mass, Secondary Ion: methods / Potassium
Isotopes (NLM Chemicals) / Potassium (NLM Chemicals) /
Rubidium (NLM Chemicals) / Sodium (NLM Chemicals) / J
(WoSType)},
cin = {ZCH / ICG-3},
ddc = {580},
cid = {I:(DE-Juel1)ZCH-20090406 / I:(DE-Juel1)ICG-3-20090406},
pnm = {Terrestrische Umwelt},
pid = {G:(DE-Juel1)FUEK407},
shelfmark = {Plant Sciences},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:18567833},
pmc = {pmc:PMC2492657},
UT = {WOS:000258184800029},
doi = {10.1104/pp.107.109215},
url = {https://juser.fz-juelich.de/record/62912},
}