TY  - JOUR
AU  - Mohrlüder, J.
AU  - Schwarten, M.
AU  - Willbold, D.
TI  - Structure and potential functions of GABARAP
JO  - The FEBS journal
VL  - 276
SN  - 1742-464X
CY  - Oxford [u.a.]
PB  - Wiley-Blackwell
M1  - PreJuSER-6509
SP  - 4989 - 5005
PY  - 2009
N1  - The authors thank Sameer Singh for carefully reading the manuscript. This study was supported by a fellowship of the International Helmholtz Research School BioSoft to M. Schwarten and a research grant from the Deutsche Forschungsgemeinschaft (DFG) to D. Willbold (Wi1472/5).
AB  - The gamma-aminobutyrate type A receptor-associated protein (GABARAP) is a ubiquitin-like modifier, and is implicated in a variety of membrane trafficking and fusion events that are crucial to synaptic plasticity, autophagy and apoptosis. However, important aspects of GABARAP function and regulation remain poorly understood. We review the current state of knowledge about GABARAP, highlighting newly-identified GABARAP ligands, and discuss the possible physiological relevance of each ligand interaction.
KW  - Adaptor Proteins, Signal Transducing: chemistry
KW  - Adaptor Proteins, Signal Transducing: physiology
KW  - Animals
KW  - Calreticulin: physiology
KW  - Carrier Proteins: physiology
KW  - Humans
KW  - Ligands
KW  - Membrane Proteins: physiology
KW  - Microfilament Proteins: physiology
KW  - Microtubule-Associated Proteins: chemistry
KW  - Microtubule-Associated Proteins: physiology
KW  - Nerve Tissue Proteins: physiology
KW  - Receptors, GABA-A: physiology
KW  - Adaptor Proteins, Signal Transducing (NLM Chemicals)
KW  - Calreticulin (NLM Chemicals)
KW  - Carrier Proteins (NLM Chemicals)
KW  - GABARAP protein, human (NLM Chemicals)
KW  - GABARAPL2 protein, human (NLM Chemicals)
KW  - GABRG2 protein, human (NLM Chemicals)
KW  - GRIP1 protein, human (NLM Chemicals)
KW  - Ligands (NLM Chemicals)
KW  - Membrane Proteins (NLM Chemicals)
KW  - Microfilament Proteins (NLM Chemicals)
KW  - Microtubule-Associated Proteins (NLM Chemicals)
KW  - Nerve Tissue Proteins (NLM Chemicals)
KW  - Receptors, GABA-A (NLM Chemicals)
KW  - gephyrin (NLM Chemicals)
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:19674112
UR  - <Go to ISI:>//WOS:000269366500001
DO  - DOI:10.1111/j.1742-4658.2009.07207.x
UR  - https://juser.fz-juelich.de/record/6509
ER  -