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@ARTICLE{Wu:7024,
author = {Wu, S.S. and Chang, T.T. and Majid, A. and Caspers, S. and
Eickhoff, S. B. and Menon, V.},
title = {{F}unctional {H}eterogeneity of {I}nferior {P}arietal
{C}ortex during {M}athematical {C}ognition {A}ssessed with
{C}ytoarchitectonic {P}robability {M}aps},
journal = {Cerebral cortex},
volume = {19},
issn = {1047-3211},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {PreJuSER-7024},
pages = {2930 - 2945},
year = {2009},
note = {National Institutes of Health (HD047520 and HD059205) and
the National Science Foundation (BCS/DRL-0750340).},
abstract = {Although the inferior parietal cortex (IPC) has been
consistently implicated in mathematical cognition, the
functional roles of its subdivisions are poorly understood.
We address this problem using probabilistic
cytoarchitectonic maps of IPC subdivisions intraparietal
sulcus (IPS), angular gyrus (AG), and supramarginal gyrus.
We quantified IPC responses relative to task difficulty and
individual differences in task proficiency during mental
arithmetic (MA) tasks performed with Arabic (MA-A) and Roman
(MA-R) numerals. The 2 tasks showed similar levels of
activation in 3 distinct IPS areas, hIP1, hIP2, and hIP3,
suggesting their obligatory role in MA. Both AG areas, PGa
and PGp, were strongly deactivated in both tasks, with
stronger deactivations in posterior area PGp. Compared with
the more difficult MA-R task, the MA-A task showed greater
responses in both AG areas, but this effect was driven by
less deactivation in the MA-A task. AG deactivations showed
prominent overlap with lateral parietal nodes of the default
mode network, suggesting a nonspecific role in MA. In both
tasks, greater bilateral AG deactivation was associated with
poorer performance. Our findings suggest a close link
between IPC structure and function and they provide new
evidence for behaviorally salient functional heterogeneity
within the IPC during mathematical cognition.},
keywords = {Adolescent / Adult / Brain Mapping / Cognition: physiology
/ Female / Humans / Male / Mathematics / Models,
Neurological / Models, Statistical / Parietal Lobe:
physiology / Problem Solving: physiology / Young Adult / J
(WoSType)},
cin = {INM-2},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems},
pid = {G:(DE-Juel1)FUEK409},
shelfmark = {Neurosciences},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19406903},
pmc = {pmc:PMC2774395},
UT = {WOS:000271813900013},
doi = {10.1093/cercor/bhp063},
url = {https://juser.fz-juelich.de/record/7024},
}