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024 7 _ |2 pmid
|a pmid:20870148
024 7 _ |2 DOI
|a 10.1016/j.nucmedbio.2010.04.185
024 7 _ |2 WOS
|a WOS:000282803500001
024 7 _ |2 ISSN
|a 1872-9414
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037 _ _ |a PreJuSER-7089
041 _ _ |a eng
082 _ _ |a 610
084 _ _ |2 WoS
|a Radiology, Nuclear Medicine & Medical Imaging
100 1 _ |0 P:(DE-Juel1)131816
|a Coenen, H. H.
|b 0
|u FZJ
245 _ _ |a Fluorine-18 radiopharmaceuticals (beyond [18F]FDG) for use in oncology and neurosciences
260 _ _ |a Amsterdam [u.a.]
|b Elsevier
|c 2010
295 1 0 |a Report of an IAEA Consultants Group Meeting
300 _ _ |a 727 - 740
336 7 _ |0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
|a Journal Article
336 7 _ |2 DataCite
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|a Journal Article
336 7 _ |2 BibTeX
|a ARTICLE
336 7 _ |2 ORCID
|a JOURNAL_ARTICLE
336 7 _ |2 DRIVER
|a article
440 _ 0 |0 4644
|a Nuclear Medicine and Biology
|v 37
|x 0883-2897
|y 7
500 _ _ |a The Consultants acknowledge the IAEA for its interest and activities in this important field. The authors from the IAEA (MRAP and JJZ) thank Dr. M. Haji-Saeid, Head, Industrial Applications and Chemistry Section, Dr. M. Dondi, Head, Nuclear Medicine Section, and Dr N. Ramamoorthy, Director-NAPC, International Atomic Energy Agency for their support and encouragement.
520 _ _ |a Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ((18)F) tracers that can be used for PET studies in the fields of oncology and neurosciences. However, most of the (18)F-tracers other than 2-deoxy-2-[18F]fluoro-D-glucose (FDG) are in less than optimum human use and there is considerable scope to bring potentially useful (18)F-tracers to clinical investigation stage. The International Atomic Energy Agency (IAEA) convened a consultants' group meeting to review the current status of (18)F-based radiotracers and to suggest means for accelerating their use for diagnostic applications. The consultants reviewed the developments including the synthetic approaches for the preparation of (18)F-tracers for oncology and neurosciences. A selection of three groups of (18)F-tracers that are useful either in oncology or in neurosciences was done based on well-defined criteria such as application, lack of toxicity, availability of precursors and ease of synthesis. Based on the recommendations of the consultants' group meeting, IAEA started a coordinated research project on "Development of (18)F radiopharmaceuticals (beyond [(18)F]FDG) for use in oncology and neurosciences" in which 14 countries are participating in a 3-year collaborative program. The outcomes of the coordinated research project are expected to catalyze the wider application of several more (18)F-radiopharmaceuticals beyond FDG for diagnostic applications in oncology and neurosciences.
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588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Animals
650 _ 2 |2 MeSH
|a Fluorodeoxyglucose F18: diagnostic use
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Neoplasms: radionuclide imaging
650 _ 2 |2 MeSH
|a Nervous System Diseases: radionuclide imaging
650 _ 2 |2 MeSH
|a Radiopharmaceuticals: diagnostic use
650 _ 7 |0 0
|2 NLM Chemicals
|a Radiopharmaceuticals
650 _ 7 |0 63503-12-8
|2 NLM Chemicals
|a Fluorodeoxyglucose F18
650 _ 7 |2 WoSType
|a J
700 1 _ |0 P:(DE-HGF)0
|a Elsinga, P.H.
|b 1
700 1 _ |0 P:(DE-HGF)0
|a Iwata, R.
|b 2
700 1 _ |0 P:(DE-HGF)0
|a Kilbourn, M.R.
|b 3
700 1 _ |0 P:(DE-HGF)0
|a Pillai, M.R.A.
|b 4
700 1 _ |0 P:(DE-HGF)0
|a Rajan, M.G.R.
|b 5
700 1 _ |0 P:(DE-HGF)0
|a Wagner, H.N.
|b 6
700 1 _ |0 P:(DE-HGF)0
|a Zaknun, J.
|b 7
773 _ _ |0 PERI:(DE-600)1498538-x
|a 10.1016/j.nucmedbio.2010.04.185
|g Vol. 37, p. 727 - 740
|p 727 - 740
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|t Nuclear medicine and biology
|v 37
|x 1872-9614
|y 2010
856 7 _ |u http://dx.doi.org/10.1016/j.nucmedbio.2010.04.185
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