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| 001 | 7139 | ||
| 005 | 20200402205724.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:19462014 |
| 024 | 7 | _ | |2 DOI |a 10.1039/b900425d |
| 024 | 7 | _ | |2 WOS |a WOS:000266269500002 |
| 037 | _ | _ | |a PreJuSER-7139 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 540 |
| 084 | _ | _ | |2 WoS |a Biochemistry & Molecular Biology |
| 100 | 1 | _ | |0 P:(DE-Juel1)VDB77156 |a Thielmann, Y. |b 0 |u FZJ |
| 245 | _ | _ | |a Structural characterization of GABARAP-ligand interactions |
| 260 | _ | _ | |a Cambridge |b Royal Society of Chemistry |c 2009 |
| 300 | _ | _ | |a 575 - 579 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |0 20661 |a Molecular BioSystems |v 5 |x 1742-206X |
| 500 | _ | _ | |a O.H.W. is grateful to Georg Buldt for continuous generous support. Moreover, assistance by the beamline staff at ESRF (Grenoble, France) is acknowledged. This study was supported by a research grant from the Deutsche Forschungsgemeinschaft to D. W. (Wi1472/5). |
| 520 | _ | _ | |a The GABA(A) receptor-associated protein (GABARAP) plays an important role in intracellular trafficking of several proteins. It undergoes a C-terminal lipidation process that enables anchoring in the cytosolic leaflet of cellular membranes. While the three-dimensional structure of GABARAP itself has been determined, structural investigation of complexes with its interaction partners has just commenced. Studies with indole derivatives revealed that GABARAP features two hydrophobic binding sites (hp1 and hp2). These also play an essential role in complex formation with the native ligand calreticulin. Furthermore, a model of hexameric N-ethylmaleimide-sensitive factor (NSF) suggests that binding of GABARAP to this molecular machine may involve a similar site. Since hp1 and hp2 are highly conserved throughout the GABARAP family, the relevance of the structural data presented here is likely to extend to GABARAP homologues. |
| 536 | _ | _ | |0 G:(DE-Juel1)FUEK409 |2 G:(DE-HGF) |a Funktion und Dysfunktion des Nervensystems |c P33 |x 0 |
| 536 | _ | _ | |0 G:(DE-Juel1)FUEK443 |2 G:(DE-HGF) |a Programm Biosoft |c N03 |x 1 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Amino Acid Sequence |
| 650 | _ | 2 | |2 MeSH |a Animals |
| 650 | _ | 2 | |2 MeSH |a Calreticulin: chemistry |
| 650 | _ | 2 | |2 MeSH |a Calreticulin: metabolism |
| 650 | _ | 2 | |2 MeSH |a Clathrin Heavy Chains: chemistry |
| 650 | _ | 2 | |2 MeSH |a Clathrin Heavy Chains: metabolism |
| 650 | _ | 2 | |2 MeSH |a Humans |
| 650 | _ | 2 | |2 MeSH |a Ligands |
| 650 | _ | 2 | |2 MeSH |a Models, Molecular |
| 650 | _ | 2 | |2 MeSH |a Protein Binding |
| 650 | _ | 2 | |2 MeSH |a Protein Structure, Tertiary |
| 650 | _ | 2 | |2 MeSH |a Receptors, GABA-A: chemistry |
| 650 | _ | 2 | |2 MeSH |a Receptors, GABA-A: metabolism |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Calreticulin |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Ligands |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Receptors, GABA-A |
| 650 | _ | 7 | |0 114899-12-6 |2 NLM Chemicals |a Clathrin Heavy Chains |
| 650 | _ | 7 | |2 WoSType |a J |
| 700 | 1 | _ | |0 P:(DE-Juel1)131988 |a Weiergräber, O.H. |b 1 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)132012 |a Mohrlüder, J. |b 2 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)132029 |a Willbold, D. |b 3 |u FZJ |
| 773 | _ | _ | |0 PERI:(DE-600)2188635-0 |a 10.1039/b900425d |g Vol. 5, p. 575 - 579 |p 575 - 579 |q 5<575 - 579 |t Molecular BioSystems |v 5 |x 1742-206X |y 2009 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1039/b900425d |
| 909 | C | O | |o oai:juser.fz-juelich.de:7139 |p VDB |
| 913 | 1 | _ | |0 G:(DE-Juel1)FUEK409 |a DE-HGF |b Gesundheit |k P33 |l Funktion und Dysfunktion des Nervensystems |v Funktion und Dysfunktion des Nervensystems |x 0 |
| 913 | 1 | _ | |0 G:(DE-Juel1)FUEK443 |a DE-HGF |b Schlüsseltechnologien |k N03 |l BioSoft |v Programm Biosoft |x 1 |z entfällt |
| 914 | 1 | _ | |y 2009 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 920 | 1 | _ | |d 31.12.2010 |g ISB |k ISB-3 |l Strukturbiochemie |0 I:(DE-Juel1)VDB942 |x 0 |
| 920 | 1 | _ | |d 31.12.2010 |g ISB |k ISB-2 |l Molekulare Biophysik |0 I:(DE-Juel1)ISB-2-20090406 |x 1 |
| 920 | 1 | _ | |0 I:(DE-82)080012_20140620 |k JARA-HPC |l Jülich Aachen Research Alliance - High-Performance Computing |g JARA |x 2 |
| 970 | _ | _ | |a VDB:(DE-Juel1)115667 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
| 980 | _ | _ | |a I:(DE-Juel1)ISB-2-20090406 |
| 980 | _ | _ | |a I:(DE-82)080012_20140620 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
| 981 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
| 981 | _ | _ | |a I:(DE-Juel1)ISB-2-20090406 |
| 981 | _ | _ | |a I:(DE-Juel1)VDB1346 |
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