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@ARTICLE{Wilms:7895,
author = {Wilms, M. and Eickhoff, S. B. and Hömke, L. and Rottschy,
C. and Kujovic, M. and Amunts, K. and Fink, G. R.},
title = {{C}omparison of functional and cytoarchitectonic maps of
human visual areas {V}1, {V}2, {V}3d, {V}3v, and {V}4(v)},
journal = {NeuroImage},
volume = {49},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {PreJuSER-7895},
pages = {1171 - 1179},
year = {2010},
note = {We are grateful to our colleagues from the MR group of the
institute for Neurosciences and Medicine for their
assistance in acquiring the fMRI data. G.R.F. was supported
by the Deutsche Forschungsgemeinschaft. S.B.E. was supported
by the Human Brain Project (R01-MH074457-01A1) and the
Helmholtz Initiative on Systems-Biology "The Human Brain
Model." This work was part of a Human Brain
Project/Neuroinformatics Research Grant funded by the
National Institute of Biomedical Imaging and Bioengineering,
the National Institute of Neurological Disorders and Stroke,
and the National Institute of Mental Health (K.A.).},
abstract = {Cytoarchitectonic maps of human striate and extrastriate
visual cortex based upon post-mortem brains can be
correlated with functionally defined cortical areas using,
for example, fMRI. We here assess the correspondence of
anatomical maps of the visual cortex with functionally
defined in vivo visual areas using retinotopic mapping. To
this end, anatomical maximum probability maps (aMPM) derived
from individual cytoarchitectonic maps of striate and
extrastriate visual areas were compared with functional
localisers for the early visual areas. Using fMRI, we
delineated dorsal and ventral human retinotopic areas V1,
V2, and V3, as well as a quarter-field visual field
representation lateral to V3v, V4(v), in 24 healthy
subjects. Based on these individual definitions, a
functional maximum probability map (fMPM) was then computed
in analogy to the aMPM. Functional and anatomical MPMs were
highly correlated at group level: $78.5\%$ of activated
voxels in the fMPM were correctly assigned by the aMPM. The
group aMPM was less effective in predicting functional
retinotopic areas in the individual brain due to the large
inter-individual variability in the location and extent of
visual areas (mean overlap $32-69\%).$ We conclude that
cytoarchitectonic maps of striate and extrastriate visual
areas may provide a valuable method for assigning functional
group activations and thus add valuable a priori knowledge
to the analysis of functional imaging data of the visual
cortex.},
keywords = {Adult / Brain Mapping / Female / Humans / Male / Photic
Stimulation / Probability / Visual Cortex: cytology / Visual
Cortex: physiology / Visual Pathways: cytology / Visual
Pathways: physiology / Visual Perception: physiology / Young
Adult / J (WoSType)},
cin = {INM-1 / INM-2 / INM-3 / JARA-BRAIN},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-2-20090406 /
I:(DE-Juel1)INM-3-20090406 / $I:(DE-82)080010_20140620$},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89572 - (Dys-)function and Plasticity (POF2-89572)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89572},
shelfmark = {Neurosciences / Neuroimaging / Radiology, Nuclear Medicine
$\&$ Medical Imaging},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19800409},
UT = {WOS:000272808400003},
doi = {10.1016/j.neuroimage.2009.09.063},
url = {https://juser.fz-juelich.de/record/7895},
}