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@ARTICLE{Koutsioumpas:807087,
author = {Koutsioumpas, Alexandros and Jaksch, Sebastian and Pérez,
Javier},
title = {{DENFERT} version 2: extension of ab initio structural
modelling of hydrated biomolecules to the case of
small-angle neutron scattering data},
journal = {Journal of applied crystallography},
volume = {49},
number = {2},
issn = {1600-5767},
address = {Copenhagen},
publisher = {Munksgaard},
reportid = {FZJ-2016-02115},
pages = {690 - 695},
year = {2016},
abstract = {Following the introduction of the program DENFERT
[Koutsioubas $\&$ Pérez (2013). J. Appl. Cryst. 46,
1884–1888 ], which takes into account the hydration layer
around solvated biological molecules during ab initio
restorations of low-resolution molecular envelopes from
small-angle X-ray scattering data, the present work
introduces the second version of the program, which provides
the ability to treat neutron scattering data sets. By
considering a fully interconnected and hydrated model during
the entire minimization process, it has been possible to
simplify the user input and reach more objective shape
reconstructions. Additionally, a new method is implemented
for the subtraction of the contribution of internal
inhomogeneities of biomolecules to the measured scattering.
Validation of the overall approach is performed by
successfully recovering the shape of various protein
molecules from experimental neutron and X-ray solution
scattering data.},
cin = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
(München) ; JCNS-FRM-II / Neutronenstreuung ; JCNS-1},
ddc = {540},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106},
pnm = {6215 - Soft Matter, Health and Life Sciences (POF3-621) /
6G15 - FRM II / MLZ (POF3-6G15) / 6G4 - Jülich Centre for
Neutron Research (JCNS) (POF3-623)},
pid = {G:(DE-HGF)POF3-6215 / G:(DE-HGF)POF3-6G15 /
G:(DE-HGF)POF3-6G4},
experiment = {EXP:(DE-MLZ)KWS1-20140101 / EXP:(DE-MLZ)MARIA-20140101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000373702000043},
doi = {10.1107/S1600576716003393},
url = {https://juser.fz-juelich.de/record/807087},
}