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@ARTICLE{Kuzmanovic:809514,
author = {Kuzmanovic, Bojana and Jefferson, Anneli and Vogeley, Kai},
title = {{T}he role of the neural reward circuitry in
self-referential optimistic belief updates},
journal = {NeuroImage},
volume = {133},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2016-02602},
pages = {151 - 162},
year = {2016},
abstract = {People are motivated to adopt the most favorable beliefs
about their future because positive beliefs are experienced
as rewarding. However, it is so far inconclusive whether
brain regions known to represent reward values are involved
in the generation of optimistically biased belief updates.
To address this question, we investigated neural correlates
of belief updates that result in relatively better future
outlooks, and therefore imply a positive subjective value of
the judgment outcome. Participants estimated the probability
of experiencing different adverse future events. After being
provided with population base rates of these events, they
had the opportunity to update their initial estimates.
Participants made judgments concerning themselves or a
similar other, and were confronted with desirable or
undesirable base rates (i.e., lower or higher than their
initial estimates).Belief updates were smaller following
undesirable than desirable information, and this optimism
bias was stronger for judgments regarding oneself than
others. During updating, the positive value of self-related
updates was reflected by neural activity in the subgenual
ventromedial prefrontal cortex (vmPFC) that increased both
with increasing sizes of favorable updates, and with
decreasing sizes of unfavorable updates. During the
processing of self-related undesirable base rates,
increasing activity in a network including the dorsomedial
PFC, hippocampus, thalamus and ventral striatum predicted
decreasing update sizes.Thus, key regions of the neural
reward circuitry contributed to the generation of
optimistically biased self-referential belief updates. While
the vmPFC tracked subjective values of belief updates, a
network including the ventral striatum was involved in
neglecting information calling for unfavorable updates.},
cin = {INM-8 / INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-8-20090406 / I:(DE-Juel1)INM-3-20090406},
pnm = {574 - Theory, modelling and simulation (POF3-574)},
pid = {G:(DE-HGF)POF3-574},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000377048600014},
pubmed = {pmid:26883063},
doi = {10.1016/j.neuroimage.2016.02.014},
url = {https://juser.fz-juelich.de/record/809514},
}