000810729 001__ 810729
000810729 005__ 20210129223514.0
000810729 0247_ $$2doi$$a10.1016/j.neurobiolaging.2016.04.010
000810729 0247_ $$2ISSN$$a0197-4580
000810729 0247_ $$2ISSN$$a1558-1497
000810729 0247_ $$2WOS$$aWOS:000378058500011
000810729 0247_ $$2altmetric$$aaltmetric:6867999
000810729 0247_ $$2pmid$$apmid:27318139
000810729 037__ $$aFZJ-2016-03321
000810729 082__ $$a610
000810729 1001_ $$0P:(DE-HGF)0$$aDillen, Kim N. H.$$b0$$eCorresponding author
000810729 245__ $$aAberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer's disease
000810729 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2016
000810729 3367_ $$2DRIVER$$aarticle
000810729 3367_ $$2DataCite$$aOutput Types/Journal article
000810729 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1466688453_30007
000810729 3367_ $$2BibTeX$$aARTICLE
000810729 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000810729 3367_ $$00$$2EndNote$$aJournal Article
000810729 520__ $$aThe posterior cingulate cortex (PCC) is a key hub of the default mode network, a resting-state network involved in episodic memory, showing functional connectivity (FC) changes in Alzheimer's disease (AD). However, PCC is a cytoarchitectonically heterogeneous region. Specifically, the retrosplenial cortex (RSC), often subsumed under the PCC, is an area functionally and microanatomically distinct from PCC. To investigate FC patterns of RSC and PCC separately, we used resting-state functional magnetic resonance imaging in healthy aging participants, patients with subjective cognitive impairment, and prodromal AD. Compared to the other 2 groups, we found higher FC from RSC to frontal cortex in subjective cognitive impairment but higher FC to occipital cortex in prodromal AD. Conversely, FC from PCC to the lingual gyrus was higher in prodromal AD. Furthermore, data indicate that RSC and PCC are characterized by differential FC patterns represented by hub-specific interactions with memory and attentions scores in prodromal AD compared to cognitively normal individuals, possibly reflecting compensatory mechanisms for RSC and neurodegenerative processes for PCC. Data thus confirm and extend previous studies suggesting that the RSC is functionally distinct from PCC.
000810729 536__ $$0G:(DE-HGF)POF3-572$$a572 - (Dys-)function and Plasticity (POF3-572)$$cPOF3-572$$fPOF III$$x0
000810729 588__ $$aDataset connected to CrossRef
000810729 7001_ $$0P:(DE-HGF)0$$aJacobs, Heidi I. L.$$b1
000810729 7001_ $$0P:(DE-Juel1)131730$$aKukolja, Juraj$$b2$$ufzj
000810729 7001_ $$0P:(DE-Juel1)156372$$avon Reutern, Boris$$b3
000810729 7001_ $$0P:(DE-Juel1)167565$$aRichter, Nils$$b4$$ufzj
000810729 7001_ $$0P:(DE-HGF)0$$aOnur, Özgür A.$$b5
000810729 7001_ $$0P:(DE-Juel1)162382$$aDronse, Julian$$b6$$ufzj
000810729 7001_ $$0P:(DE-Juel1)131777$$aLangen, Karl-Josef$$b7$$ufzj
000810729 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b8$$ufzj
000810729 773__ $$0PERI:(DE-600)1498414-3$$a10.1016/j.neurobiolaging.2016.04.010$$gVol. 44, p. 114 - 126$$p114 - 126$$tNeurobiology of aging$$v44$$x0197-4580$$y2016
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.pdf$$yRestricted
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.gif?subformat=icon$$xicon$$yRestricted
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.jpg?subformat=icon-1440$$xicon-1440$$yRestricted
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.jpg?subformat=icon-180$$xicon-180$$yRestricted
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.jpg?subformat=icon-640$$xicon-640$$yRestricted
000810729 8564_ $$uhttps://juser.fz-juelich.de/record/810729/files/1-s2.0-S0197458016300379-main.pdf?subformat=pdfa$$xpdfa$$yRestricted
000810729 909CO $$ooai:juser.fz-juelich.de:810729$$pVDB
000810729 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131730$$aForschungszentrum Jülich$$b2$$kFZJ
000810729 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)167565$$aForschungszentrum Jülich$$b4$$kFZJ
000810729 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)162382$$aForschungszentrum Jülich$$b6$$kFZJ
000810729 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131777$$aForschungszentrum Jülich$$b7$$kFZJ
000810729 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich$$b8$$kFZJ
000810729 9131_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0
000810729 9141_ $$y2016
000810729 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000810729 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000810729 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bNEUROBIOL AGING : 2014
000810729 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000810729 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000810729 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000810729 915__ $$0StatID:(DE-HGF)0550$$2StatID$$aNo Authors Fulltext
000810729 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bNEUROBIOL AGING : 2014
000810729 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000810729 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000810729 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000810729 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000810729 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000810729 920__ $$lyes
000810729 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0
000810729 9201_ $$0I:(DE-Juel1)INM-4-20090406$$kINM-4$$lPhysik der Medizinischen Bildgebung$$x1
000810729 980__ $$ajournal
000810729 980__ $$aVDB
000810729 980__ $$aUNRESTRICTED
000810729 980__ $$aI:(DE-Juel1)INM-3-20090406
000810729 980__ $$aI:(DE-Juel1)INM-4-20090406
000810729 981__ $$aI:(DE-Juel1)INM-4-20090406