% IMPORTANT: The following is UTF-8 encoded. This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.
@ARTICLE{Dillen:810729,
author = {Dillen, Kim N. H. and Jacobs, Heidi I. L. and Kukolja,
Juraj and von Reutern, Boris and Richter, Nils and Onur,
Özgür A. and Dronse, Julian and Langen, Karl-Josef and
Fink, Gereon R.},
title = {{A}berrant functional connectivity differentiates
retrosplenial cortex from posterior cingulate cortex in
prodromal {A}lzheimer's disease},
journal = {Neurobiology of aging},
volume = {44},
issn = {0197-4580},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2016-03321},
pages = {114 - 126},
year = {2016},
abstract = {The posterior cingulate cortex (PCC) is a key hub of the
default mode network, a resting-state network involved in
episodic memory, showing functional connectivity (FC)
changes in Alzheimer's disease (AD). However, PCC is a
cytoarchitectonically heterogeneous region. Specifically,
the retrosplenial cortex (RSC), often subsumed under the
PCC, is an area functionally and microanatomically distinct
from PCC. To investigate FC patterns of RSC and PCC
separately, we used resting-state functional magnetic
resonance imaging in healthy aging participants, patients
with subjective cognitive impairment, and prodromal AD.
Compared to the other 2 groups, we found higher FC from RSC
to frontal cortex in subjective cognitive impairment but
higher FC to occipital cortex in prodromal AD. Conversely,
FC from PCC to the lingual gyrus was higher in prodromal AD.
Furthermore, data indicate that RSC and PCC are
characterized by differential FC patterns represented by
hub-specific interactions with memory and attentions scores
in prodromal AD compared to cognitively normal individuals,
possibly reflecting compensatory mechanisms for RSC and
neurodegenerative processes for PCC. Data thus confirm and
extend previous studies suggesting that the RSC is
functionally distinct from PCC.},
cin = {INM-3 / INM-4},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000378058500011},
pubmed = {pmid:27318139},
doi = {10.1016/j.neurobiolaging.2016.04.010},
url = {https://juser.fz-juelich.de/record/810729},
}