%0 Conference Paper
%A Machtens, Jan-Philipp
%A Briones, R.
%A de Groot, B. L.
%A Fahlke, Christoph
%T Gating charge calculations: Probing voltage-sensing proteins through computational electrophysiology
%J Biophysical journal
%V 110
%N 3
%@ 0006-3495
%C Cambridge, Mass.
%I Cell Press
%M FZJ-2016-04364
%P 106A
%D 2016
%X Sensitivity to voltage stimuli is a defining property of electrical excitability and is found in ion channels with dedicated voltage sensors, but also in other channels, transporters and even metabotropic receptors. Voltage dependence is conferred by an effective transmembrane charge transfer that can be attributed to global or localized conformational changes, ion or ligand binding, protonation or changes in water accessibility that reshape the electric field.
%B 60th Annual Meeting of the Biophysical-Society
%C 27 Feb 2016 - 2 Mar 2016, Los Angeles, CA (USA)
Y2 27 Feb 2016 - 2 Mar 2016
M2 Los Angeles, CA, USA
%F PUB:(DE-HGF)16 ; PUB:(DE-HGF)8
%9 Journal ArticleContribution to a conference proceedings
%U <Go to ISI:>//WOS:000375093800033
%R 10.1016/j.bpj.2015.11.628
%U https://juser.fz-juelich.de/record/817706