TY  - CONF
AU  - Machtens, Jan-Philipp
AU  - Briones, R.
AU  - de Groot, B. L.
AU  - Fahlke, Christoph
TI  - Gating charge calculations: Probing voltage-sensing proteins through computational electrophysiology
JO  - Biophysical journal
VL  - 110
IS  - 3
SN  - 0006-3495
CY  - Cambridge, Mass.
PB  - Cell Press
M1  - FZJ-2016-04364
SP  - 106A
PY  - 2016
AB  - Sensitivity to voltage stimuli is a defining property of electrical excitability and is found in ion channels with dedicated voltage sensors, but also in other channels, transporters and even metabotropic receptors. Voltage dependence is conferred by an effective transmembrane charge transfer that can be attributed to global or localized conformational changes, ion or ligand binding, protonation or changes in water accessibility that reshape the electric field.
T2  - 60th Annual Meeting of the Biophysical-Society
CY  - 27 Feb 2016 - 2 Mar 2016, Los Angeles, CA (USA)
Y2  - 27 Feb 2016 - 2 Mar 2016
M2  - Los Angeles, CA, USA
LB  - PUB:(DE-HGF)16 ; PUB:(DE-HGF)8
UR  - <Go to ISI:>//WOS:000375093800033
DO  - DOI:10.1016/j.bpj.2015.11.628
UR  - https://juser.fz-juelich.de/record/817706
ER  -