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@INPROCEEDINGS{Machtens:817706,
author = {Machtens, Jan-Philipp and Briones, R. and de Groot, B. L.
and Fahlke, Christoph},
title = {{G}ating charge calculations: {P}robing voltage-sensing
proteins through computational electrophysiology},
journal = {Biophysical journal},
volume = {110},
number = {3},
issn = {0006-3495},
address = {Cambridge, Mass.},
publisher = {Cell Press},
reportid = {FZJ-2016-04364},
pages = {106A},
year = {2016},
abstract = {Sensitivity to voltage stimuli is a defining property of
electrical excitability and is found in ion channels with
dedicated voltage sensors, but also in other channels,
transporters and even metabotropic receptors. Voltage
dependence is conferred by an effective transmembrane charge
transfer that can be attributed to global or localized
conformational changes, ion or ligand binding, protonation
or changes in water accessibility that reshape the electric
field.},
month = {Feb},
date = {2016-02-27},
organization = {60th Annual Meeting of the
Biophysical-Society, Los Angeles, CA
(USA), 27 Feb 2016 - 2 Mar 2016},
cin = {ICS-4},
ddc = {570},
cid = {I:(DE-Juel1)ICS-4-20110106},
pnm = {553 - Physical Basis of Diseases (POF3-553)},
pid = {G:(DE-HGF)POF3-553},
typ = {PUB:(DE-HGF)16 / PUB:(DE-HGF)8},
UT = {WOS:000375093800033},
doi = {10.1016/j.bpj.2015.11.628},
url = {https://juser.fz-juelich.de/record/817706},
}