Home > Publications database > Gating charge calculations: Probing voltage-sensing proteins through computational electrophysiology > print |
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100 | 1 | _ | |a Machtens, Jan-Philipp |0 P:(DE-Juel1)156429 |b 0 |e Corresponding author |
111 | 2 | _ | |a 60th Annual Meeting of the Biophysical-Society |c Los Angeles, CA |d 2016-02-27 - 2016-03-02 |w USA |
245 | _ | _ | |a Gating charge calculations: Probing voltage-sensing proteins through computational electrophysiology |
260 | _ | _ | |a Cambridge, Mass. |c 2016 |b Cell Press |
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520 | _ | _ | |a Sensitivity to voltage stimuli is a defining property of electrical excitability and is found in ion channels with dedicated voltage sensors, but also in other channels, transporters and even metabotropic receptors. Voltage dependence is conferred by an effective transmembrane charge transfer that can be attributed to global or localized conformational changes, ion or ligand binding, protonation or changes in water accessibility that reshape the electric field. |
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