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000819317 1001_ $$0P:(DE-Juel1)159136$$aMigunov, Vadim$$b0$$eCorresponding author
000819317 245__ $$aRapid low dose electron tomography using a direct electron detection camera
000819317 260__ $$aLondon$$bNature Publishing Group$$c2015
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000819317 520__ $$aWe demonstrate the ability to record a tomographic tilt series containing 3487 images in only 3.5 s by using a direct electron detector in a transmission electron microscope. The electron dose is lower by at least one order of magnitude when compared with that used to record a conventional tilt series of fewer than 100 images in 15–60 minutes and the overall signal-to-noise ratio is greater than 4. Our results, which are illustrated for an inorganic nanotube, are important for ultra-low-dose electron tomography of electron-beam-sensitive specimens and real-time dynamic electron tomography of nanoscale objects with sub-ms temporal resolution.
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000819317 7001_ $$0P:(DE-HGF)0$$aRyll, Henning$$b1
000819317 7001_ $$0P:(DE-HGF)0$$aZhuge, Xiaodong$$b2
000819317 7001_ $$0P:(DE-HGF)0$$aSimson, Martin$$b3
000819317 7001_ $$0P:(DE-HGF)0$$aStrüder, Lothar$$b4
000819317 7001_ $$0P:(DE-HGF)0$$aBatenburg, K. Joost$$b5
000819317 7001_ $$0P:(DE-Juel1)130723$$aHouben, Lothar$$b6
000819317 7001_ $$0P:(DE-Juel1)144121$$aDunin-Borkowski, Rafal$$b7
000819317 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/srep14516$$gVol. 5, p. 14516 -$$p14516$$tScientific reports$$v5$$x2045-2322$$y2015
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