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100 1 _ |a Migunov, Vadim
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245 _ _ |a Rapid low dose electron tomography using a direct electron detection camera
260 _ _ |a London
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520 _ _ |a We demonstrate the ability to record a tomographic tilt series containing 3487 images in only 3.5 s by using a direct electron detector in a transmission electron microscope. The electron dose is lower by at least one order of magnitude when compared with that used to record a conventional tilt series of fewer than 100 images in 15–60 minutes and the overall signal-to-noise ratio is greater than 4. Our results, which are illustrated for an inorganic nanotube, are important for ultra-low-dose electron tomography of electron-beam-sensitive specimens and real-time dynamic electron tomography of nanoscale objects with sub-ms temporal resolution.
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700 1 _ |a Zhuge, Xiaodong
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700 1 _ |a Simson, Martin
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