%0 Journal Article
%A Safarik, Ivo
%A Stepanek, Miroslav
%A Uchman, Mariusz
%A Slouf, Miroslav
%A Baldikova, Eva
%A Nydlova, Leona
%A Pospiskova, Kristyna
%A Safarikova, Mirka
%T Composite particles formed by complexation of poly(methacrylic acid) — stabilized magnetic fluid with chitosan: Magnetic material for bioapplications
%J Materials science and engineering / C
%V 67
%@ 0928-4931
%C Amsterdam
%I Elsevier
%M FZJ-2016-05278
%P 486 - 492
%D 2016
%X A simple procedure for the synthesis of magnetic fluid (ferrofluid) stabilized by poly(methacrylic acid) has been developed. This ferrofluid was used to prepare a novel type of magnetically responsive chitosan-based composite material. Both ferrofluid and magnetic chitosan composite were characterized by a combination of microscopy (optical microscopy, TEM, SEM), scattering (static and dynamic light scattering, SANS) and spectroscopy (FTIR) techniques. Magnetic chitosan was found to be a perspective material for various bioapplications, especially as a magnetic carrier for immobilization of enzymes and cells. Lipase from Candida rugosa was covalently attached after cross-linking and activation of chitosan using glutaraldehyde. Baker's yeast cells (Saccharomyces cerevisiae) were incorporated into the chitosan composite during its preparation; both biocatalysts were active after reaction with appropriate substrates.
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000378952800055
%$ pmid:27287146
%R 10.1016/j.msec.2016.05.017
%U https://juser.fz-juelich.de/record/819671