TY - JOUR
AU - Safarik, Ivo
AU - Stepanek, Miroslav
AU - Uchman, Mariusz
AU - Slouf, Miroslav
AU - Baldikova, Eva
AU - Nydlova, Leona
AU - Pospiskova, Kristyna
AU - Safarikova, Mirka
TI - Composite particles formed by complexation of poly(methacrylic acid) — stabilized magnetic fluid with chitosan: Magnetic material for bioapplications
JO - Materials science and engineering / C
VL - 67
SN - 0928-4931
CY - Amsterdam
PB - Elsevier
M1 - FZJ-2016-05278
SP - 486 - 492
PY - 2016
AB - A simple procedure for the synthesis of magnetic fluid (ferrofluid) stabilized by poly(methacrylic acid) has been developed. This ferrofluid was used to prepare a novel type of magnetically responsive chitosan-based composite material. Both ferrofluid and magnetic chitosan composite were characterized by a combination of microscopy (optical microscopy, TEM, SEM), scattering (static and dynamic light scattering, SANS) and spectroscopy (FTIR) techniques. Magnetic chitosan was found to be a perspective material for various bioapplications, especially as a magnetic carrier for immobilization of enzymes and cells. Lipase from Candida rugosa was covalently attached after cross-linking and activation of chitosan using glutaraldehyde. Baker's yeast cells (Saccharomyces cerevisiae) were incorporated into the chitosan composite during its preparation; both biocatalysts were active after reaction with appropriate substrates.
LB - PUB:(DE-HGF)16
UR - <Go to ISI:>//WOS:000378952800055
C6 - pmid:27287146
DO - DOI:10.1016/j.msec.2016.05.017
UR - https://juser.fz-juelich.de/record/819671
ER -