TY  - JOUR
AU  - AlTarabeen, Mousa
AU  - Daletos, Georgios
AU  - Ebrahim, Weaam
AU  - Müller, Werner E. G.
AU  - Hartmann, Rudolf
AU  - Lin, Wehan
AU  - Proksch, Peter
TI  - Ircinal E, a New Manzamine Derivative frim the Indonesian Marine Sponge Acanthostrongylophora ingens
JO  - Natural product communications
VL  - 10
SN  - 1555-9475
CY  - Westerville, Ohio
PB  - NPC
M1  - FZJ-2016-05391
SP  - 1951-1953
PY  - 2015
AB  - Chemical investigation of the MeOH extract of the sponge Acanthostrongylophora ingens afforded the new manzamine derivative ircinal E (1), in addition tosix known metabolites (2–7). The structure of the new compound was unequivocally elucidated using one- and two-dimensional NMR spectroscopy, as wellas high-resolution mass spectrometry. Compounds 1–6 exhibited strong to moderate cytotoxicity against the murine lymphoma L5178Y cell line with IC50values ranging from 2.8 to 21.7 μM.
LB  - PUB:(DE-HGF)16
UR  - https://juser.fz-juelich.de/record/819796
ER  -