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| Hauptseite > Publikationsdatenbank > Ircinal E, a New Manzamine Derivative frim the Indonesian Marine Sponge Acanthostrongylophora ingens > print |
| Hauptseite > Publikationsdatenbank > Ircinal E, a New Manzamine Derivative frim the Indonesian Marine Sponge Acanthostrongylophora ingens > print |
| 001 | 819796 | ||
| 005 | 20210129224351.0 | ||
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| 100 | 1 | _ | |a AlTarabeen, Mousa |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Ircinal E, a New Manzamine Derivative frim the Indonesian Marine Sponge Acanthostrongylophora ingens |
| 260 | _ | _ | |a Westerville, Ohio |c 2015 |b NPC |
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| 520 | _ | _ | |a Chemical investigation of the MeOH extract of the sponge Acanthostrongylophora ingens afforded the new manzamine derivative ircinal E (1), in addition tosix known metabolites (2–7). The structure of the new compound was unequivocally elucidated using one- and two-dimensional NMR spectroscopy, as wellas high-resolution mass spectrometry. Compounds 1–6 exhibited strong to moderate cytotoxicity against the murine lymphoma L5178Y cell line with IC50values ranging from 2.8 to 21.7 μM. |
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