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@INPROCEEDINGS{Diaz:820578,
      author       = {Diaz, Sandra and Nowke, Christian and Peyser, Alexander and
                      Weyers, Benjamin and Hentschel, Bernd and Morrison, Abigail
                      and Kuhlen, Torsten W.},
      title        = {{M}ultiscale approach to explore the relationships between
                      connectivity and function in whole brain simulations},
      reportid     = {FZJ-2016-05852},
      year         = {2016},
      abstract     = {To better understand the relationship between connectivity
                      and function in the brain at different scales, in this work
                      we show the results of using point-neuron network
                      simulations to complement connectivity information from
                      whole brain simulations based on a dynamic neuron mass
                      model. In our multiscale approach, we simulate a whole brain
                      parcellated into 68 regions where each region is modeled as
                      a dynamic neuron mass, and in parallel, we also model each
                      region as small 200 point-neuron populations in NEST.
                      Structural plasticity in NEST is then used to calculate
                      inner connectivity of each region with the aid of an
                      interactive tool designed for visualizing and steering the
                      algorithm. Using this approach, the fitting and parameter
                      space exploration times are reduced and a new way to explore
                      the impact of connectivity in function at different scales
                      is presented.},
      month         = {Oct},
      date          = {2016-10-12},
      organization  = {HBP Summit 2016, Florence (Italy), 12
                       Oct 2016 - 14 Oct 2016},
      subtyp        = {Other},
      cin          = {JSC / JARA-HPC},
      cid          = {I:(DE-Juel1)JSC-20090406 / $I:(DE-82)080012_20140620$},
      pnm          = {574 - Theory, modelling and simulation (POF3-574) / 511 -
                      Computational Science and Mathematical Methods (POF3-511) /
                      571 - Connectivity and Activity (POF3-571) / W2Morrison -
                      W2/W3 Professorinnen Programm der Helmholtzgemeinschaft
                      (B1175.01.12) / Virtual Connectomics - Deutschland - USA
                      Zusammenarbeit in Computational Science: Mechanistische
                      Zusammenhänge zwischen Struktur und funktioneller Dynamik
                      im menschlichen Gehirn (BMBF-01GQ1504B) / SLNS - SimLab
                      Neuroscience (Helmholtz-SLNS)},
      pid          = {G:(DE-HGF)POF3-574 / G:(DE-HGF)POF3-511 /
                      G:(DE-HGF)POF3-571 / G:(DE-HGF)B1175.01.12 /
                      G:(DE-Juel1)BMBF-01GQ1504B / G:(DE-Juel1)Helmholtz-SLNS},
      typ          = {PUB:(DE-HGF)24},
      doi          = {10.12751/nncn.bc2016.0059},
      url          = {https://juser.fz-juelich.de/record/820578},
}