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@INPROCEEDINGS{Buitenhuis:823981,
author = {Buitenhuis, Johan and Anop, Hanna},
title = {{P}olyelectrolyte complexes from mixtures of oppositely
charged filamentous viruses},
reportid = {FZJ-2016-06607},
year = {2016},
abstract = {The fd virus is a filamentous bacteriophage with a length
of 880 nm and a diameter of 6.6 nm, that was first isolated
from sewage. The virus consists of a single-stranded
circular DNA molecule packed in a cylindrical capsid of
2,700 identical major coat proteins and a few minor coat
proteins at the ends. In the present study the virus is used
as a material, i.e. we are not interested in the biological
properties, apart from the fact that it can be grown in
certain bacteria. Solutions of these viruses can form liquid
crystalline phases, are well defined and therefore have been
used many times as a model system. By chemical modification
of the surface proteins the viruses can be modified, to
obtain new properties. An interesting possibility is the
modification of the carboxylic groups on the surface of the
fd virus by using carbodiimide chemistry to obtain
dispersions of charge reversed fd viruses (i.e. positively
charged at neutral pH) [1]. As expected, adding dilute
solutions of positively charged and negatively charged fd
together can result in flocculation. This charge reversal
can be combined with a steric stabilization by poly(ethylene
glycol) grafting, so that the above mentioned flocculation
can be made adjustable and reversible by changing the ionic
strength in the solution [1], yielding an interesting model
system for the formation of polyelectrolyte complexes (PECs)
[2]. Here results on the formation of polyelectrolyte
complexes will be presented and the charge of the (modified)
viruses is modeled and compared to results from free
solution electrophoresis [3].Acknowledgements. We thank M.P.
Lettinga and P.R. Lang for useful suggestions[1] Z. Zhang,
J. Buitenhuis, A. Cukkemane, M. Brocker, M. Bott and J.K.G.
Dhont, Langmuir 2010, 26, 10593.[2] J. van der Gucht, E.
Spruijt, M. Lemmers and M.A. Cohen Stuart, J. Colloid
Interface Sci. 2011, 361, 407.[3] J. Buitenhuis, Langmuir
2012, 28, 13354.},
month = {Sep},
date = {2016-09-01},
organization = {Ostwald Colloquium of the German
Colloid Society, RWTH Aachen (Germany),
1 Sep 2016 - 2 Sep 2016},
subtyp = {After Call},
cin = {ICS-3},
cid = {I:(DE-Juel1)ICS-3-20110106},
pnm = {551 - Functional Macromolecules and Complexes (POF3-551)},
pid = {G:(DE-HGF)POF3-551},
typ = {PUB:(DE-HGF)6},
url = {https://juser.fz-juelich.de/record/823981},
}