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@ARTICLE{Zischler:825303,
      author       = {Zischler, Johannes and Krapf, Philipp and Richarz, Raphael
                      and Zlatopolskiy, Boris D. and Neumaier, Bernd},
      title        = {{A}utomated synthesis of 4-[$^{18}${F}]fluoroanisole,
                      [$^{18}${F}]{DAA}1106 and 4-[$^{18}${F}]{FP}he using
                      {C}u-mediated radiofluorination under “minimalist”
                      conditions},
      journal      = {Applied radiation and isotopes},
      volume       = {115},
      issn         = {0969-8043},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2016-07767},
      pages        = {133 - 137},
      year         = {2016},
      abstract     = {The application of the “minimalist” approach to
                      Cu-mediated radiofluorination allows the efficient
                      preparation of 18F-labeled arenes regardless of their
                      electronic properties. The implementation of this
                      methodology on a commercially available synthesis module
                      (hotboxthree, Scintomics, Germany) enabled the automated
                      production of 4-[18F]fluoroanisole as well as the clinically
                      relevant PET-tracers, 4-[18F]FPhe and [18F]DAA1106, in
                      radiochemical yields of $41–61\%$ and radiochemical
                      purities of $>95\%$ within 30–60 min. These results
                      demonstrated the high efficacy and versatility of the
                      developed method that will open up opportunities for a broad
                      application of Cu-mediated radiofluorination in
                      PET-chemistry.},
      cin          = {INM-5},
      ddc          = {530},
      cid          = {I:(DE-Juel1)INM-5-20090406},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000382594900022},
      doi          = {10.1016/j.apradiso.2016.04.030},
      url          = {https://juser.fz-juelich.de/record/825303},
}