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@ARTICLE{Galldiks:826480,
      author       = {Galldiks, Norbert and Law, Ian and Pope, Whitney B. and
                      Arbizu, Javier and Langen, Karl-Josef},
      title        = {{T}he use of amino acid {PET} and conventional {MRI} for
                      monitoring of brain tumor therapy},
      journal      = {NeuroImage: Clinical},
      volume       = {13},
      issn         = {2213-1582},
      address      = {[Amsterdam u.a.]},
      publisher    = {Elsevier},
      reportid     = {FZJ-2017-00705},
      pages        = {386 - 394},
      year         = {2017},
      abstract     = {Routine diagnostics and treatment monitoring of brain
                      tumors is usually based on contrast-enhanced MRI. However,
                      the capacity of conventional MRI to differentiate tumor
                      tissue from posttherapeutic effects following neurosurgical
                      resection, chemoradiation, alkylating chemotherapy,
                      radiosurgery, and/or immunotherapy may be limited. Metabolic
                      imaging using PET can provide relevant additional
                      information on tumor metabolism, which allows for more
                      accurate diagnostics especially in clinically equivocal
                      situations. This review article focuses predominantly on the
                      amino acid PET tracers 11C-methyl-l-methionine (MET),
                      O-(2-[18F]fluoroethyl)-l-tyrosine (FET) and
                      3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (FDOPA) and
                      summarizes investigations regarding monitoring of brain
                      tumor therapy.},
      cin          = {INM-3 / INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000401413700045},
      pubmed       = {pmid:28116231},
      doi          = {10.1016/j.nicl.2016.12.020},
      url          = {https://juser.fz-juelich.de/record/826480},
}