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000828033 0247_ $$2doi$$a10.1080/15622975.2016.1268715
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000828033 1001_ $$aGiegling, Ina$$b0
000828033 245__ $$aGenetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics
000828033 260__ $$aAbingdon$$bTaylor & Francis Group$$c2017
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000828033 520__ $$aAbstractObjectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general population. The relative contribution of genetic factors has been estimated to be up to 80%. The mode of inheritance is complex, non-Mendelian, and in most cases involving the combined action of large numbers of genes.Methods: This review summarises recent efforts to identify genetic variants associated with schizophrenia detected, e.g., through genome-wide association studies, studies on copy-number variants or next-generation sequencing.Results: A large, new body of evidence on genetics of schizophrenia has accumulated over recent years. Many new robustly associated genetic loci have been detected. Furthermore, there is consensus that at least a dozen microdeletions and microduplications contribute to the disease. Genetic overlap between schizophrenia, other psychiatric disorders, and neurodevelopmental syndromes raised new questions regarding the current classification of psychiatric and neurodevelopmental diseases.
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000828033 7001_ $$aHosak, Ladislav$$b1
000828033 7001_ $$aMössner, Rainald$$b2
000828033 7001_ $$aSerretti, Alessandro$$b3
000828033 7001_ $$aBellivier, Frank$$b4
000828033 7001_ $$aClaes, Stephan$$b5
000828033 7001_ $$aCollier, David A.$$b6
000828033 7001_ $$aCorrales, Alejo$$b7
000828033 7001_ $$aDeLisi, Lynn E.$$b8
000828033 7001_ $$aGallo, Carla$$b9
000828033 7001_ $$aGill, Michael$$b10
000828033 7001_ $$aKennedy, James L.$$b11
000828033 7001_ $$aLeboyer, Marion$$b12
000828033 7001_ $$0P:(DE-Juel1)159384$$aMaier, Wolfgang$$b13
000828033 7001_ $$aMarquez, Miguel$$b14
000828033 7001_ $$aMassat, Isabelle$$b15
000828033 7001_ $$aMors, Ole$$b16
000828033 7001_ $$aMuglia, Pierandrea$$b17
000828033 7001_ $$aNöthen, Markus M.$$b18
000828033 7001_ $$aOspina-Duque, Jorge$$b19
000828033 7001_ $$aOwen, Michael J.$$b20
000828033 7001_ $$aPropping, Peter$$b21
000828033 7001_ $$aShi, YongYong$$b22
000828033 7001_ $$aSt Clair, David$$b23
000828033 7001_ $$aThibaut, Florence$$b24
000828033 7001_ $$0P:(DE-Juel1)140234$$aCichon, Sven$$b25
000828033 7001_ $$aMendlewicz, Julien$$b26
000828033 7001_ $$aO'Donovan, Michael C.$$b27
000828033 7001_ $$0P:(DE-HGF)0$$aRujescu, Dan$$b28$$eCorresponding author
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