000829769 001__ 829769 000829769 005__ 20210129230341.0 000829769 037__ $$aFZJ-2017-03403 000829769 041__ $$aEnglish 000829769 1001_ $$0P:(DE-Juel1)168124$$aGutberlet, Thomas$$b0$$eCorresponding author 000829769 1112_ $$aDPG-Frühjahrstagung 2017$$cDresden$$d2017-03-19 - 2017-03-24$$wGermany 000829769 245__ $$aAdhesion ability of angiotensin II with model membranes 000829769 260__ $$c2017 000829769 3367_ $$033$$2EndNote$$aConference Paper 000829769 3367_ $$2DataCite$$aOther 000829769 3367_ $$2BibTeX$$aINPROCEEDINGS 000829769 3367_ $$2DRIVER$$aconferenceObject 000829769 3367_ $$2ORCID$$aLECTURE_SPEECH 000829769 3367_ $$0PUB:(DE-HGF)6$$2PUB:(DE-HGF)$$aConference Presentation$$bconf$$mconf$$s1495013152_22002$$xAfter Call 000829769 520__ $$aThe octa-peptide angiotensin II (Ang II, (H2N-Asp*Arg*Val*Tyr*Ile*His*Pro*Phe*COOH)) is one of the key player on blood pressure regulationin mammals. Predominantly binding to the Angiotensin type 1and 2 receptors, the hormone is one of several peptide ligands bindingto G protein coupled receptors (GPCR). The chemical nature of theamino acid sequence has an impact on the behavior in the proximityof membranes, demonstrated using different membrane model systemsand biophysical methods. Applying electrochemical impedance spectroscopyand small angle x-ray scattering a detailed view on the adhesionof the peptide with model membrane surfaces was performed.The role of specific amino acids involved in the interaction with thephospholipid head group were investigated and, studying a truncatedversion of Ang II, Ang (1-7), the key role of the C-terminal phenylalaninewas proven. 000829769 536__ $$0G:(DE-HGF)POF3-6G4$$a6G4 - Jülich Centre for Neutron Research (JCNS) (POF3-623)$$cPOF3-623$$fPOF III$$x0 000829769 536__ $$0G:(DE-HGF)POF3-6G15$$a6G15 - FRM II / MLZ (POF3-6G15)$$cPOF3-6G15$$fPOF III$$x1 000829769 65027 $$0V:(DE-MLZ)SciArea-160$$2V:(DE-HGF)$$aBiology$$x0 000829769 65017 $$0V:(DE-MLZ)GC-130-2016$$2V:(DE-HGF)$$aHealth and Life$$x0 000829769 693__ $$0EXP:(DE-MLZ)External-20140101$$5EXP:(DE-MLZ)External-20140101$$eMeasurement at external facility$$x0 000829769 7001_ $$0P:(DE-HGF)0$$aPreu, Julia$$b1 000829769 7001_ $$0P:(DE-HGF)0$$aTiefenauer, Louis$$b2 000829769 909CO $$ooai:juser.fz-juelich.de:829769$$pVDB$$pVDB:MLZ 000829769 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)168124$$aForschungszentrum Jülich$$b0$$kFZJ 000829769 9131_ $$0G:(DE-HGF)POF3-623$$1G:(DE-HGF)POF3-620$$2G:(DE-HGF)POF3-600$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF3-6G4$$aDE-HGF$$bForschungsbereich Materie$$lVon Materie zu Materialien und Leben$$vFacility topic: Neutrons for Research on Condensed Matter$$x0 000829769 9131_ $$0G:(DE-HGF)POF3-6G15$$1G:(DE-HGF)POF3-6G0$$2G:(DE-HGF)POF3-600$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF3-6G15$$aDE-HGF$$bForschungsbereich Materie$$lGroßgeräte: Materie$$vFRM II / MLZ$$x1 000829769 9141_ $$y2017 000829769 9201_ $$0I:(DE-Juel1)JCNS-FRM-II-20110218$$kJCNS (München) ; Jülich Centre for Neutron Science JCNS (München) ; JCNS-FRM-II$$lJCNS-FRM-II$$x0 000829769 980__ $$aconf 000829769 980__ $$aVDB 000829769 980__ $$aI:(DE-Juel1)JCNS-FRM-II-20110218 000829769 980__ $$aUNRESTRICTED