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000830385 041__ $$aEnglish
000830385 1001_ $$0P:(DE-Juel1)166572$$aNiether, Doreen$$b0$$eCorresponding author$$ufzj
000830385 1112_ $$a116th General Assembly of the  German Bunsen Society for Physical Chemistry$$cKaiserslautern$$d2017-05-25 - 2017-05-27$$gBunsentagung 2017$$wGermany
000830385 245__ $$aThermophoresis and the ‘Origin-of-Life’ concept
000830385 260__ $$c2017
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000830385 520__ $$aFormamide is of special interest in the 'origin-of-life' concept as it forms a number of prebiotic molecules under catalytic conditions and at sufficiently high concentrations [1]. For nucleotides and short DNA strands, numerical finite-element calculations have shown that a high degree of accumulation in hydrothermal pores occurs [2]. Using thermophoretic data of the formamide/water system measured with Infra-Red Thermal Diffusion Forced Rayleigh Scattering, we show that the same combination of thermophoresis and convection in hydrothermal pores leads to accumulation of formamide up to concentrations high enough to initiate synthesis of prebiotic nucleobases. The high degree of formamide accumulation is due to an unusual temperature and concentration dependence of the thermophoretic behaviour of formamide. Starting with a formamide concentration of 10-3 wt%, estimated to be typical in shallow lakes on early earth [3], the accumulation-fold in part of the pores increases strongly with increasing aspect ratio of the pores, and saturates to highly concentrated aqueous formamide solutions of approximately 85 wt% at large aspect ratios [4].  Time dependent studies show that these high concentrations are reached after 45-90 days. To understand the dependence of the accumulation on pore geometry, we derived a heuristic model to illuminate the process.[1] Pino, S.; Sponer, J. E.; Costanzo, G.; Saladino, R. and Di Mauro, E.; Life, 5, 372-384, 2015. [2] Baaske, P.; Weinert, F. M.; Duhr, S.; Lemke, K. H.; Russell, M. J. and Braun,D.; Proc. Natl. Acad. Sci. USA, 104, 9346-9351, 2007.[3] Miyakawa, S.; Cleaves, H. J. and Miller, S. L.; Origins Life Evol. Biosphere, 32, 195-208, 2002.[4] Niether, D.; Afanasenkau, D.; Dhont, J.K.G.; Wiegand, S.; Proc. Natl. Acad. Sci. USA, 113, 4272–4277, 2016.
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000830385 7001_ $$0P:(DE-Juel1)144600$$aAfanasenkau, Dzmitry$$b1
000830385 7001_ $$0P:(DE-Juel1)130616$$aDhont, Jan K.G.$$b2$$ufzj
000830385 7001_ $$0P:(DE-Juel1)131034$$aWiegand, Simone$$b3$$ufzj
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