TY  - JOUR
AU  - Kireev, Dmitry
AU  - Seyock, Silke
AU  - Lewen, Johannes
AU  - Maybeck, Vanessa
AU  - Wolfrum, Bernhard
AU  - Offenhäusser, Andreas
TI  - Graphene Multielectrode Arrays as a Versatile Tool for Extracellular Measurements552
JO  - Advanced healthcare materials
VL  - 6
IS  - 12
SN  - 2192-2640
CY  - Weinheim
PB  - Wiley-VCH
M1  - FZJ-2017-04104
SP  - 1601433 -
PY  - 2017
AB  - Graphene multielectrode arrays (GMEAs) presented in this work are used for cardio and neuronal extracellular recordings. The advantages of the graphene as a part of the multielectrode arrays are numerous: from a general flexibility and biocompatibility to the unique electronic properties of graphene. The devices used for extensive in vitro studies of a cardiac-like cell line and cortical neuronal networks show excellent ability to extracellularly detect action potentials with signal to noise ratios in the range of 45 ± 22 for HL-1 cells and 48 ± 26 for spontaneous bursting/spiking neuronal activity. Complex neuronal bursting activity patterns as well as a variety of characteristic shapes of HL-1 action potentials are recorded with the GMEAs. This paper illustrates that the potential applications of the GMEAs in biological and medical research are still numerous and diverse.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000403787500006
C6  - pmid:28371490
DO  - DOI:10.1002/adhm.201601433
UR  - https://juser.fz-juelich.de/record/834103
ER  -