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100 1 _ |a Kireev, Dmitry
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245 _ _ |a Graphene Multielectrode Arrays as a Versatile Tool for Extracellular Measurements552
260 _ _ |a Weinheim
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520 _ _ |a Graphene multielectrode arrays (GMEAs) presented in this work are used for cardio and neuronal extracellular recordings. The advantages of the graphene as a part of the multielectrode arrays are numerous: from a general flexibility and biocompatibility to the unique electronic properties of graphene. The devices used for extensive in vitro studies of a cardiac-like cell line and cortical neuronal networks show excellent ability to extracellularly detect action potentials with signal to noise ratios in the range of 45 ± 22 for HL-1 cells and 48 ± 26 for spontaneous bursting/spiking neuronal activity. Complex neuronal bursting activity patterns as well as a variety of characteristic shapes of HL-1 action potentials are recorded with the GMEAs. This paper illustrates that the potential applications of the GMEAs in biological and medical research are still numerous and diverse.
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700 1 _ |a Lewen, Johannes
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700 1 _ |a Maybeck, Vanessa
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700 1 _ |a Wolfrum, Bernhard
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700 1 _ |a Offenhäusser, Andreas
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