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100 1 _ |a Mishin, A. V.
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245 _ _ |a Expression and purification of an engineered human endothelin receptor B in a monomeric form
260 _ _ |a Dordrecht []
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520 _ _ |a In humans, two endothelin receptors, ETa and ETb, are activated by three endogenous 21-mer cyclic peptides, ET-1, ET-2, and ET-3, which control various physiological processes, including vasoconstriction, vasodilation, and stimulation of cell proliferation. The first stage of this study it to produce a stable solubilized and purified receptor in a monodisperse state. This article is focused on the engineering, expression, purification, and characterization of the endothelin receptor B for subsequent structural and functional studies.
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700 1 _ |a Luginina, A. P.
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700 1 _ |a Potapenko, A. P.
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700 1 _ |a Borshchevskiy, Valentin
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700 1 _ |a Katritch, V.
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700 1 _ |a Edelweiss, E.
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700 1 _ |a Okhrimenko, I. S.
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