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@ARTICLE{Mengotti:834557,
      author       = {Mengotti, Paola and Dombert, Pascasie L. and Fink, Gereon
                      Rudolf and Vossel, Simone},
      title        = {{D}isruption of the {R}ight {T}emporoparietal {J}unction
                      {I}mpairs {P}robabilistic {B}elief {U}pdating},
      journal      = {The journal of neuroscience},
      volume       = {37},
      number       = {22},
      issn         = {0270-6474},
      address      = {Washington, DC},
      publisher    = {Soc.},
      reportid     = {FZJ-2017-04485},
      pages        = {5419 - 5428},
      year         = {2017},
      abstract     = {Generating and updating probabilistic models of the
                      environment is a fundamental modus operandi of the human
                      brain. Although crucial for various cognitive functions, the
                      neural mechanisms of these inference processes remain to be
                      elucidated. Here, we show the causal involvement of the
                      right temporoparietal junction (rTPJ) in updating
                      probabilistic beliefs and we provide new insights into the
                      chronometry of the process by combining online transcranial
                      magnetic stimulation (TMS) with computational modeling of
                      behavioral responses. Female and male participants performed
                      a modified location-cueing paradigm, where false information
                      about the percentage of cue validity $(\%CV)$ was provided
                      in half of the experimental blocks to prompt updating of
                      prior expectations. Online double-pulse TMS over rTPJ 300 ms
                      (but not 50 ms) after target appearance selectively
                      decreased participants' updating of false prior beliefs
                      concerning $\%CV,$ reflected in a decreased learning rate of
                      a Rescorla–Wagner model. Online TMS over rTPJ also
                      impacted on participants' explicit beliefs, causing them to
                      overestimate $\%CV.$ These results confirm the involvement
                      of rTPJ in updating of probabilistic beliefs, thereby
                      advancing our understanding of this area's function during
                      cognitive processing.},
      cin          = {INM-3},
      ddc          = {590},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000402808900004},
      pubmed       = {pmid:28473647},
      doi          = {10.1523/JNEUROSCI.3683-16.2017},
      url          = {https://juser.fz-juelich.de/record/834557},
}