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@ARTICLE{Weichselbaum:834626,
author = {Weichselbaum, Ewald and Österbauer, Maria and Knyazev,
Denis G. and Batishchev, Oleg V. and Akimov, Sergey A. and
Hai Nguyen, Trung and Zhang, Chao and Knör, Günther and
Agmon, Noam and Carloni, Paolo and Pohl, Peter},
title = {{O}rigin of proton affinity to membrane/water interfaces},
journal = {Scientific reports},
volume = {7},
number = {1},
issn = {2045-2322},
address = {London},
publisher = {Nature Publishing Group},
reportid = {FZJ-2017-04534},
pages = {4553},
year = {2017},
abstract = {Proton diffusion along biological membranes is vitally
important for cellular energetics. Here we extended previous
time-resolved fluorescence measurements to study the time
and temperature dependence of surface proton transport. We
determined the Gibbs activation energy barrier ΔG‡r that
opposes proton surface-to-bulk release from Arrhenius plots
of (i) protons’ surface diffusion constant and (ii) the
rate coefficient for proton surface-to-bulk release. The
large size of ΔG‡r disproves that quasi-equilibrium
exists in our experiments between protons in the
near-membrane layers and in the aqueous bulk. Instead,
non-equilibrium kinetics describes the proton travel between
the site of its photo-release and its arrival at a distant
membrane patch at different temperatures. ΔG‡r contains
only a minor enthalpic contribution that roughly corresponds
to the breakage of a single hydrogen bond. Thus, our
experiments reveal an entropic trap that ensures channeling
of highly mobile protons along the membrane interface in the
absence of potent acceptors.},
cin = {IAS-5 / INM-9},
ddc = {000},
cid = {I:(DE-Juel1)IAS-5-20120330 / I:(DE-Juel1)INM-9-20140121},
pnm = {899 - ohne Topic (POF3-899)},
pid = {G:(DE-HGF)POF3-899},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000404618400067},
doi = {10.1038/s41598-017-04675-9},
url = {https://juser.fz-juelich.de/record/834626},
}