% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Maus:834700,
      author       = {Maus, Volker and You, Seunghwa and Kalkan, Alev and
                      Borggrefe, Jan and Kabbasch, Christoph and Barnikol, Utako
                      Birgit and Stetefeld, Henning and Dohmen, Christian and
                      Liebig, Thomas and Fink, Gereon Rudolf and Mpotsaris,
                      Anastasios},
      title        = {{I}ncomplete {L}arge {V}essel {O}cclusions in {M}echanical
                      {T}hrombectomy: {A}n {I}ndependent {P}redictor of
                      {F}avorable {O}utcome in {I}schemic {S}troke},
      journal      = {Cerebrovascular diseases},
      volume       = {44},
      number       = {3-4},
      issn         = {1421-9786},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {FZJ-2017-04603},
      pages        = {113 - 121},
      year         = {2017},
      abstract     = {Background and Purpose: Cerebral large vessel occlusion
                      (LVO) in acute ischemic stroke (AIS) may be complete (CLVO)
                      or incomplete (ILVO). The influence of ILVO on clinical
                      outcome after mechanical thrombectomy (MT) remains unclear.
                      We investigated primarily the clinical outcome in patients
                      with AIS due to ILVO or CLVO. Methods: Five hundred three
                      consecutive AIS patients with LVO treated with
                      stent-retriever or direct aspiration-based MT between 2010
                      and 2016 were analyzed. The primary endpoint was favorable
                      clinical outcome (modified Rankin Scale ≤2) at 90 days;
                      secondary endpoints were periprocedural parameters. Results:
                      Forty-nine patients $(11.3\%)$ with a median National
                      Institutes of Health Stroke Scale (NIHSS) of 11 presented
                      with ILVO and the remainder presented with CLVO and median
                      NIHSS of 15 (p < 0.001). The median groin
                      puncture-to-reperfusion time was 30 vs. 67 min, respectively
                      (p < 0.001). Successful reperfusion was reached in 47 out of
                      49 ILVO $(95.9\%)$ vs. 298 out of 381 CLVO $(78.2\%;$ p <
                      0.005) with less retrieval maneuvers (1.7 ± 2.2 vs. 3.0 ±
                      2.5; p < 0.001). The favorable outcome at 90 days was $81\%$
                      in patients with ILVO vs. $29.1\%$ in CLVO (p < 0.001);
                      respective all-cause mortality rates were 6.4 vs. $28.5\%$
                      (p < 0.001). Periprocedural complications $(6.9\%)$ occurred
                      exclusively in CLVO patients (p < 0.05). ILVO was associated
                      with favorable clinical outcome independent of age and NIHSS
                      in multivariate logistic regression both in the anterior (OR
                      3.6; $95\%$ CI 1.8-6.9; p < 0.001) and posterior circulation
                      (OR 3.5; $95\%$ CI 1.8-6.9; p < 0.001). Conclusions: AIS due
                      to ILVO is frequent and is associated with a nearly
                      threefold higher chance of favorable clinical outcome at 90
                      days, independent of age and initial NIHSS compared to
                      CLVO.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {572 - (Dys-)function and Plasticity (POF3-572)},
      pid          = {G:(DE-HGF)POF3-572},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28605743},
      UT           = {WOS:000417567200004},
      doi          = {10.1159/000477499},
      url          = {https://juser.fz-juelich.de/record/834700},
}