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000834701 1001_ $$0P:(DE-Juel1)144215$$aMauler, Jörg$$b0$$eCorresponding author
000834701 245__ $$aDissociated Crossed Speech Areas in a Tumour Patient
000834701 260__ $$aBasel$$bKarger$$c2017
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000834701 520__ $$aIn the past, the eloquent areas could be deliberately localised by the invasive Wada test. The very rare cases of dissociated crossed speech areas were accidentally found based on the clinical symptomatology. Today functional magnetic resonance imaging (fMRI)-based imaging can be employed to non-invasively localise the eloquent areas in brain tumour patients for therapy planning. A 41-year-old, left-handed man with a low-grade glioma in the left frontal operculum extending to the insular cortex, tension headaches, and anomic aphasia over 5 months underwent a pre-operative speech area localisation fMRI measurement, which revealed the evidence of the transhemispheric disposition, where the dominant Wernicke speech area is located on the left and the Broca’s area is strongly lateralised to the right hemisphere. The outcome of the Wada test and the intraoperative cortico-subcortical stimulation mapping were congruent with this finding. After tumour removal, language area function was fully preserved. Upon the occurrence of brain tumours with a risk of impaired speech function, the rare dissociate crossed speech areas disposition may gain a clinically relevant meaning by allowing for more extended tumour removal. Hence, for its identification, diagnostics which take into account both brain hemispheres, such as fMRI, are recommended.
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000834701 7001_ $$0P:(DE-Juel1)131781$$aNeuner, Irene$$b1$$ufzj
000834701 7001_ $$0P:(DE-HGF)0$$aNeuloh, Georg$$b2
000834701 7001_ $$0P:(DE-HGF)0$$aFimm, Bruno$$b3
000834701 7001_ $$0P:(DE-Juel1)131752$$aBoers, Frank$$b4$$ufzj
000834701 7001_ $$0P:(DE-HGF)0$$aWiesmann, Martin$$b5
000834701 7001_ $$0P:(DE-HGF)0$$aClusmann, Hans$$b6
000834701 7001_ $$0P:(DE-Juel1)131777$$aLangen, Karl-Josef$$b7$$ufzj
000834701 7001_ $$0P:(DE-Juel1)131794$$aShah, N. J.$$b8$$ufzj
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