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@ARTICLE{Mauler:834701,
      author       = {Mauler, Jörg and Neuner, Irene and Neuloh, Georg and Fimm,
                      Bruno and Boers, Frank and Wiesmann, Martin and Clusmann,
                      Hans and Langen, Karl-Josef and Shah, N. J.},
      title        = {{D}issociated {C}rossed {S}peech {A}reas in a {T}umour
                      {P}atient},
      journal      = {Case reports in neurology},
      volume       = {9},
      number       = {2},
      issn         = {1662-680X},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {FZJ-2017-04604},
      pages        = {131 - 136},
      year         = {2017},
      abstract     = {In the past, the eloquent areas could be deliberately
                      localised by the invasive Wada test. The very rare cases of
                      dissociated crossed speech areas were accidentally found
                      based on the clinical symptomatology. Today functional
                      magnetic resonance imaging (fMRI)-based imaging can be
                      employed to non-invasively localise the eloquent areas in
                      brain tumour patients for therapy planning. A 41-year-old,
                      left-handed man with a low-grade glioma in the left frontal
                      operculum extending to the insular cortex, tension
                      headaches, and anomic aphasia over 5 months underwent a
                      pre-operative speech area localisation fMRI measurement,
                      which revealed the evidence of the transhemispheric
                      disposition, where the dominant Wernicke speech area is
                      located on the left and the Broca’s area is strongly
                      lateralised to the right hemisphere. The outcome of the Wada
                      test and the intraoperative cortico-subcortical stimulation
                      mapping were congruent with this finding. After tumour
                      removal, language area function was fully preserved. Upon
                      the occurrence of brain tumours with a risk of impaired
                      speech function, the rare dissociate crossed speech areas
                      disposition may gain a clinically relevant meaning by
                      allowing for more extended tumour removal. Hence, for its
                      identification, diagnostics which take into account both
                      brain hemispheres, such as fMRI, are recommended.},
      cin          = {INM-4 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$},
      pnm          = {573 - Neuroimaging (POF3-573)},
      pid          = {G:(DE-HGF)POF3-573},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000411508700003},
      pubmed       = {pmid:28626411},
      doi          = {10.1159/000475882},
      url          = {https://juser.fz-juelich.de/record/834701},
}