% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Gro:835094,
      author       = {Groß, Felicitas and Rudolf, Eva-Esther and Thiele, Björn
                      and Durner, Jörg and Astier, Jeremy},
      title        = {{C}opper amine oxidase 8 regulates arginine-dependent
                      nitric oxide production in {A}rabidopsis thaliana},
      journal      = {The journal of experimental botany},
      volume       = {68},
      number       = {9},
      issn         = {1460-2431},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {FZJ-2017-04962},
      pages        = {2149 - 2162},
      year         = {2017},
      abstract     = {Nitric oxide (NO) is a key signaling molecule in plants,
                      regulating a wide range of physiological processes. However,
                      its origin in plants remains unclear. It can be generated
                      from nitrite through a reductive pathway, notably via the
                      action of the nitrate reductase (NR), and evidence suggests
                      an additional oxidative pathway, involving arginine. From an
                      initial screen of potential Arabidopsis thaliana mutants
                      impaired in NO production, we identified copper amine
                      oxidase 8 (CuAO8). Two cuao8 mutant lines displayed a
                      decreased NO production in seedlings after elicitor
                      treatment and salt stress. The NR-dependent pathway was not
                      responsible for the impaired NO production as no change in
                      NR activity was found in the mutants. However, total
                      arginase activity was strongly increased in cuao8 knockout
                      mutants after salt stress. Moreover, NO production could be
                      restored in the mutants by arginase inhibition or arginine
                      addition. Furthermore, arginine supplementation reversed the
                      root growth phenotype observed in the mutants. These results
                      demonstrate that CuAO8 participates in NO production by
                      influencing arginine availability through the modulation of
                      arginase activity. The influence of CuAO8 on
                      arginine-dependent NO synthesis suggests a new regulatory
                      pathway for NO production in plants.},
      cin          = {IBG-2},
      ddc          = {580},
      cid          = {I:(DE-Juel1)IBG-2-20101118},
      pnm          = {582 - Plant Science (POF3-582)},
      pid          = {G:(DE-HGF)POF3-582},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000402272700008},
      pubmed       = {pmid:28383668},
      doi          = {10.1093/jxb/erx105},
      url          = {https://juser.fz-juelich.de/record/835094},
}