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@ARTICLE{Clemens:836272,
      author       = {Clemens, Benjamin and Wagels, Lisa and Bauchmüller,
                      Magdalena and Bergs, Rene and Habel, Ute and Kohn, Nils},
      title        = {{A}lerted default mode: functional connectivity changes in
                      the aftermath of social stress},
      journal      = {Scientific reports},
      volume       = {7},
      issn         = {2045-2322},
      address      = {London},
      publisher    = {Nature Publishing Group},
      reportid     = {FZJ-2017-05393},
      pages        = {40180 -},
      year         = {2017},
      abstract     = {Stress affects the brain at a network level: the salience
                      network is supposedly upregulated, while at the same time
                      the executive control network is downregulated. While
                      theoretically described, the effects in the aftermath of
                      stress have thus far not been tested empirically. Here, we
                      compared for the first time resting-state functional
                      connectivity in a large sample of healthy volunteers before
                      and after a mild social stressor. Following the theoretical
                      prediction, we focused on connectivity of the salience
                      network (SN), the executive control network (ECN) and the
                      default mode network (DMN). The DMN exhibited increased
                      resting-state functional connectivity following the
                      cyberball task to the key nodes of the SN, namely the dorsal
                      anterior cingulate cortex (dACC) and the anterior insula, as
                      well as sensorimotor regions and higher-order visual areas.
                      We conclude that this increased connectivity of the DMN with
                      key nodes of the SN and regions responsible for preparatory
                      motor activity and visual motion processing indicates a
                      shift towards an ‘alerted default mode’ in the aftermath
                      of stress. This brain response may be triggered or
                      aggravated by (social) stress induced by the cyberball task,
                      enabling individuals to better reorient attention, detect
                      salient external stimuli, and deal with the emotional and
                      affective consequences of stress.},
      cin          = {INM-10},
      ddc          = {000},
      cid          = {I:(DE-Juel1)INM-10-20170113},
      pnm          = {89572 - (Dys-)function and Plasticity (POF2-89572)},
      pid          = {G:(DE-HGF)POF2-89572},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000391563700001},
      pubmed       = {pmid:28054651},
      doi          = {10.1038/srep40180},
      url          = {https://juser.fz-juelich.de/record/836272},
}