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@ARTICLE{Marx:836585,
      author       = {Marx, Manuel and Qi, Guanxiao and Hanganu-Opatz, Ileana L.
                      and Kilb, Werner and Luhmann, Heiko J. and Feldmeyer, Dirk},
      title        = {{N}eocortical {L}ayer 6{B} as a {R}emnant of the {S}ubplate
                      - {A} {M}orphological {C}omparison},
      journal      = {Cerebral cortex},
      volume       = {27},
      number       = {2},
      issn         = {1460-2199},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {FZJ-2017-05660},
      pages        = {1011-1026},
      year         = {2017},
      abstract     = {The fate of the subplate (SP) is still a matter of debate.
                      The SP and layer 6 (which is ontogenetically the oldest and
                      innermostneocortical lamina) develop coincidentally. Yet,
                      the function of sublamina 6B is largely unknown. It has been
                      suggested that itconsists partly of neurons from the
                      transient SP, however, experimental evidence for this
                      hypothesis is still missing. To obtainfirst insights into
                      the neuronal complement of layer 6B in the somatosensory rat
                      barrel cortex, we used biocytin stainings of SPneurons (aged
                      0–4 postnatal days, PND) and layer 6B neurons (PND
                      11–35) obtained during in vitro whole-cell
                      patch-clamprecordings. Neurons were reconstructed for a
                      quantitative characterization of their axonal and dendritic
                      morphology. An unsupervised cluster analysis revealed that
                      the SP and layer 6B consist of heterogeneous but comparable
                      neuronal cell populations. Both contain 5 distinct
                      spine-bearing cell types whose relative fractions change
                      with increasing age. Pyramidal cells were more prominent in
                      layer 6B, whereas non-pyramidal neurons were less frequent.
                      Because of the high morphological similarity of SP and layer
                      6B neurons, we suggest that layer 6B consists of persistent
                      non-pyramidal neurons from the SP and cortical L6B pyramidal
                      neurons.},
      cin          = {INM-2},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {571 - Connectivity and Activity (POF3-571)},
      pid          = {G:(DE-HGF)POF3-571},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000397257600010},
      pubmed       = {pmid:26637449},
      doi          = {10.1093/cercor/bhv279},
      url          = {https://juser.fz-juelich.de/record/836585},
}